Intra-Interobserver Variability in Myocardial Perfusion and Function Interpretation and Reproducibility of QGS/QPS Software

Duygu Tokbay

Makale detayları

Intra-Interobserver Variability in Myocardial Perfusion and Function Interpretation and Reproducibility of QGS/QPS Software

Yazarlar:

Duygu Tokbay

Yayıncı:

Mersin University

Ana Başlıklar:

Cardiology | Nuclear Medicine

Dergi:

Molecular Oncologic Imaging Vol.4 Issue 3, pp.27-38

Belge Tipi:

Makale

Yayın Tarihi:

1/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001339019

pISSN:

2791-965X

Anahtar kelimeler:

Özet:

 Aim: To assess three different level experienced nuclear medicine specialists intra- and interobserver variability of semiquantitative visual interpretations of left ventricular LV myocardial perfusion, wall motion WM, and wall thickening WT in gated myocardial perfusion single- photon emission tomography gMPS, and to compare the compatibility between the observers and coronary angiography CAG reports. Methods: A 5-point perfusion scale, a 6-point scale for WM, and a 4-point scale for WT were used to score each segment. The images were interpreted 3 times at least one-month intervals separately by 3 observers. Subsequently, the visual semiquantitative summed scores for stress SSS and rest SRS were calculated by summing the respective segmental perfusion scores. Summed difference score SDS was also calculated as the difference between SSS and SRS. Both visual semiquantitative WM and WT scores were calculated from the stress images by summing all corresponding segmental scores. Results: Intraobserver agreement in the evaluation of global perfusion was statistically significant 71.9-100 . There was a significant agreement in all LAD-SSS, Cx-SSS, ve RCA-SSS interpretations. There was good agreement between 3 readings of 3 observers p0.0. Due to the high interobserver agreement levels in the global evaluation, the mean values of the 1. and the 2. interpretations mean 1.-2. int. were calculated and regional comparisons were made with this new value and the 3. interpretation. There was a a significant agreement in 3 of the regional SSS interpretations. Although lowest agreement rates were calculated in LAD artery territory, the agreement levels were statistically, and highly significant in all territories. In both Cx and RCA territories, the agreement levels were statistically significant p0.05. Conclusion: The interobserver and intraobserver agreement levels of perfusion interpretations were significant both in the global and regional base. There was a significant agreement between the visual interpretations and CAG results, especially in the Cx and RCA artery territories. The interobserver and intraobserver agreements were higher in WM scores than wall thickness scores. QPSQGS software quantitative perfusion and left ventricular ejection fraction LVEF values showed high repeatability.

 Aim: To assess three different level experienced nuclear medicine specialists intra- and interobserver variability of semiquantitative visual interpretations of left ventricular LV myocardial perfusion, wall motion WM, and wall thickening WT in gated myocardial perfusion single- photon emission tomography gMPS, and to compare the compatibility between the observers and coronary angiography CAG reports. Methods: A 5-point perfusion scale, a 6-point scale for WM, and a 4-point scale for WT were used to score each segment. The images were interpreted 3 times at least one-month intervals separately by 3 observers. Subsequently, the visual semiquantitative summed scores for stress SSS and rest SRS were calculated by summing the respective segmental perfusion scores. Summed difference score SDS was also calculated as the difference between SSS and SRS. Both visual semiquantitative WM and WT scores were calculated from the stress images by summing all corresponding segmental scores. Results: Intraobserver agreement in the evaluation of global perfusion was statistically significant 71.9-100 . There was a significant agreement in all LAD-SSS, Cx-SSS, ve RCA-SSS interpretations. There was good agreement between 3 readings of 3 observers p0.0. Due to the high interobserver agreement levels in the global evaluation, the mean values of the 1. and the 2. interpretations mean 1.-2. int. were calculated and regional comparisons were made with this new value and the 3. interpretation. There was a a significant agreement in 3 of the regional SSS interpretations. Although lowest agreement rates were calculated in LAD artery territory, the agreement levels were statistically, and highly significant in all territories. In both Cx and RCA territories, the agreement levels were statistically significant p0.05. Conclusion: The interobserver and intraobserver agreement levels of perfusion interpretations were significant both in the global and regional base. There was a significant agreement between the visual interpretations and CAG results, especially in the Cx and RCA artery territories. The interobserver and intraobserver agreements were higher in WM scores than wall thickness scores. QPSQGS software quantitative perfusion and left ventricular ejection fraction LVEF values showed high repeatability.

 Aim: To assess three different level experienced nuclear medicine specialists intra- and interobserver variability of semiquantitative visual interpretations of left ventricular LV myocardial perfusion, wall motion WM, and wall thickening WT in gated myocardial perfusion single- photon emission tomography gMPS, and to compare the compatibility between the observers and coronary angiography CAG reports. Methods: A 5-point perfusion scale, a 6-point scale for WM, and a 4-point scale for WT were used to score each segment. The images were interpreted 3 times at least one-month intervals separately by 3 observers. Subsequently, the visual semiquantitative summed scores for stress SSS and rest SRS were calculated by summing the respective segmental perfusion scores. Summed difference score SDS was also calculated as the difference between SSS and SRS. Both visual semiquantitative WM and WT scores were calculated from the stress images by summing all corresponding segmental scores. Results: Intraobserver agreement in the evaluation of global perfusion was statistically significant 71.9-100 . There was a significant agreement in all LAD-SSS, Cx-SSS, ve RCA-SSS interpretations. There was good agreement between 3 readings of 3 observers p0.0. Due to the high interobserver agreement levels in the global evaluation, the mean values of the 1. and the 2. interpretations mean 1.-2. int. were calculated and regional comparisons were made with this new value and the 3. interpretation. There was a a significant agreement in 3 of the regional SSS interpretations. Although lowest agreement rates were calculated in LAD artery territory, the agreement levels were statistically, and highly significant in all territories. In both Cx and RCA territories, the agreement levels were statistically significant p0.05. Conclusion: The interobserver and intraobserver agreement levels of perfusion interpretations were significant both in the global and regional base. There was a significant agreement between the visual interpretations and CAG results, especially in the Cx and RCA artery territories. The interobserver and intraobserver agreements were higher in WM scores than wall thickness scores. QPSQGS software quantitative perfusion and left ventricular ejection fraction LVEF values showed high repeatability.

 Aim: To assess three different level experienced nuclear medicine specialists intra- and interobserver variability of semiquantitative visual interpretations of left ventricular LV myocardial perfusion, wall motion WM, and wall thickening WT in gated myocardial perfusion single- photon emission tomography gMPS, and to compare the compatibility between the observers and coronary angiography CAG reports. Methods: A 5-point perfusion scale, a 6-point scale for WM, and a 4-point scale for WT were used to score each segment. The images were interpreted 3 times at least one-month intervals separately by 3 observers. Subsequently, the visual semiquantitative summed scores for stress SSS and rest SRS were calculated by summing the respective segmental perfusion scores. Summed difference score SDS was also calculated as the difference between SSS and SRS. Both visual semiquantitative WM and WT scores were calculated from the stress images by summing all corresponding segmental scores. Results: Intraobserver agreement in the evaluation of global perfusion was statistically significant 71.9-100 . There was a significant agreement in all LAD-SSS, Cx-SSS, ve RCA-SSS interpretations. There was good agreement between 3 readings of 3 observers p0.0. Due to the high interobserver agreement levels in the global evaluation, the mean values of the 1. and the 2. interpretations mean 1.-2. int. were calculated and regional comparisons were made with this new value and the 3. interpretation. There was a a significant agreement in 3 of the regional SSS interpretations. Although lowest agreement rates were calculated in LAD artery territory, the agreement levels were statistically, and highly significant in all territories. In both Cx and RCA territories, the agreement levels were statistically significant p0.05. Conclusion: The interobserver and intraobserver agreement levels of perfusion interpretations were significant both in the global and regional base. There was a significant agreement between the visual interpretations and CAG results, especially in the Cx and RCA artery territories. The interobserver and intraobserver agreements were higher in WM scores than wall thickness scores. QPSQGS software quantitative perfusion and left ventricular ejection fraction LVEF values showed high repeatability.

Makale detayları

Intra-Interobserver Variability in Myocardial Perfusion and Function Interpretation and Reproducibility of QGS/QPS Software

Yazarlar:

Duygu Tokbay

Yayıncı:

Mersin University

Ana Başlıklar:

Cardiology | Nuclear Medicine

Dergi:

Molecular Oncologic Imaging Vol.4 Issue 3, pp.27-38

Belge Tipi:

Makale

Yayın Tarihi:

1/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001339019

pISSN:

2791-965X

Gated myocardial perfusion single-photon emission tomography; left ventricular myocardial perfusion

wall motion

QGS/QPS Software

Sayı

Makale detayları

Intra-Interobserver Variability in Myocardial Perfusion and Function Interpretation and Reproducibility of QGS/QPS Software

Yazarlar: Duygu Tokbay

Yayıncı: Mersin University

Ana Başlıklar: Cardiology | Nuclear Medicine

Dergi: Molecular Oncologic Imaging Vol.4 Issue 3, pp.27-38

Belge Tipi: Makale

Yayın Tarihi: 1/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001339019

pISSN: 2791-965X

Gated myocardial perfusion single-photon emission tomography; left ventricular myocardial perfusion

wall motion

QGS/QPS Software

Sayı

Yazarlar:

Duygu Tokbay

Yayıncı:

Mersin University

Ana Başlıklar:

Cardiology | Nuclear Medicine

Dergi:

Molecular Oncologic Imaging Vol.4 Issue 3, pp.27-38

Belge Tipi:

Makale

Yayın Tarihi:

1/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001339019

pISSN:

2791-965X