Electrochemical Study of 17β-Estradiol and its Determination in Pharmaceutical Preparations using Square Wave Voltammetry

Bilal Yılmaz; Yücel Kadıoğlu

Makale detayları

Electrochemical Study of 17β-Estradiol and its Determination in Pharmaceutical Preparations using Square Wave Voltammetry

Yazarlar:

Bilal Yılmaz | Yücel Kadıoğlu

Yayıncı:

Turkish Chemical Society

Ana Başlıklar:

Analytical Chemistry | Electrochemistry

Dergi:

Journal of the Turkish Chemical Society Section A: Chemistry Vol.10 Issue 3, pp.589-598

Belge Tipi:

Makale

Yayın Tarihi:

8/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001292797

pISSN:

2149-0120

Anahtar kelimeler:

Özet:

 In the present study, the electroanalytical behavior of 17β-estradiol was investigated using cyclic voltammetry. The procedure was based on 17β-estradiol being electrochemically oxidized at a platinum electrode in non-aqueous solutions. At 1.47 V, the oxidation peak was noted. It was discovered that 17β-estradiols oxidation was diffusion-controlled. Additionally, a quick and easy square wave voltammetry method was developed and validated in this work to determine 17β-estradiol in pharmaceutical preparations. The calibration curve was linear at 5 and 30 µgmL concentrations. The precision was given by relative standard deviation and was less than 3.36. Accuracy was given with relative error and did not exceed 2.54. In pharmaceutical preparations, 17β-estradiol had an average recovery of 100.3. Under the chosen experimental conditions, no interference was found. The suggested method is highly accurate and precise. Therefore, the method applies to measuring 17β-estradiol in pharmaceutical formulations.

 In the present study, the electroanalytical behavior of 17β-estradiol was investigated using cyclic voltammetry. The procedure was based on 17β-estradiol being electrochemically oxidized at a platinum electrode in non-aqueous solutions. At 1.47 V, the oxidation peak was noted. It was discovered that 17β-estradiols oxidation was diffusion-controlled. Additionally, a quick and easy square wave voltammetry method was developed and validated in this work to determine 17β-estradiol in pharmaceutical preparations. The calibration curve was linear at 5 and 30 µgmL concentrations. The precision was given by relative standard deviation and was less than 3.36. Accuracy was given with relative error and did not exceed 2.54. In pharmaceutical preparations, 17β-estradiol had an average recovery of 100.3. Under the chosen experimental conditions, no interference was found. The suggested method is highly accurate and precise. Therefore, the method applies to measuring 17β-estradiol in pharmaceutical formulations.

 In the present study, the electroanalytical behavior of 17β-estradiol was investigated using cyclic voltammetry. The procedure was based on 17β-estradiol being electrochemically oxidized at a platinum electrode in non-aqueous solutions. At 1.47 V, the oxidation peak was noted. It was discovered that 17β-estradiols oxidation was diffusion-controlled. Additionally, a quick and easy square wave voltammetry method was developed and validated in this work to determine 17β-estradiol in pharmaceutical preparations. The calibration curve was linear at 5 and 30 µgmL concentrations. The precision was given by relative standard deviation and was less than 3.36. Accuracy was given with relative error and did not exceed 2.54. In pharmaceutical preparations, 17β-estradiol had an average recovery of 100.3. Under the chosen experimental conditions, no interference was found. The suggested method is highly accurate and precise. Therefore, the method applies to measuring 17β-estradiol in pharmaceutical formulations.

 In the present study, the electroanalytical behavior of 17β-estradiol was investigated using cyclic voltammetry. The procedure was based on 17β-estradiol being electrochemically oxidized at a platinum electrode in non-aqueous solutions. At 1.47 V, the oxidation peak was noted. It was discovered that 17β-estradiols oxidation was diffusion-controlled. Additionally, a quick and easy square wave voltammetry method was developed and validated in this work to determine 17β-estradiol in pharmaceutical preparations. The calibration curve was linear at 5 and 30 µgmL concentrations. The precision was given by relative standard deviation and was less than 3.36. Accuracy was given with relative error and did not exceed 2.54. In pharmaceutical preparations, 17β-estradiol had an average recovery of 100.3. Under the chosen experimental conditions, no interference was found. The suggested method is highly accurate and precise. Therefore, the method applies to measuring 17β-estradiol in pharmaceutical formulations.

Makale detayları

Electrochemical Study of 17β-Estradiol and its Determination in Pharmaceutical Preparations using Square Wave Voltammetry

Yazarlar:

Bilal Yılmaz | Yücel Kadıoğlu

Yayıncı:

Turkish Chemical Society

Ana Başlıklar:

Analytical Chemistry | Electrochemistry

Dergi:

Journal of the Turkish Chemical Society Section A: Chemistry Vol.10 Issue 3, pp.589-598

Belge Tipi:

Makale

Yayın Tarihi:

8/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001292797

pISSN:

2149-0120

17beta-estradiol

Voltammetry

Validation

Analysis

Sayı

Makale detayları

Electrochemical Study of 17β-Estradiol and its Determination in Pharmaceutical Preparations using Square Wave Voltammetry

Yazarlar: Bilal Yılmaz | Yücel Kadıoğlu

Yayıncı: Turkish Chemical Society

Ana Başlıklar: Analytical Chemistry | Electrochemistry

Dergi: Journal of the Turkish Chemical Society Section A: Chemistry Vol.10 Issue 3, pp.589-598

Belge Tipi: Makale

Yayın Tarihi: 8/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001292797

pISSN: 2149-0120

17beta-estradiol

Voltammetry

Validation

Analysis

Sayı

Yazarlar:

Bilal Yılmaz | Yücel Kadıoğlu

Yayıncı:

Turkish Chemical Society

Ana Başlıklar:

Analytical Chemistry | Electrochemistry

Dergi:

Journal of the Turkish Chemical Society Section A: Chemistry Vol.10 Issue 3, pp.589-598

Belge Tipi:

Makale

Yayın Tarihi:

8/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001292797

pISSN:

2149-0120