DESIGN AND SIMULATION OF A NOVEL C-DEP MICROFLUIDICS FOR SINGLE CELL TRAPPING

M.moghimi ZAND

doi:https://doi.org/10.18186/journal-of-thermal-engineering.330181

Makale detayları

DESIGN AND SIMULATION OF A NOVEL C-DEP MICROFLUIDICS FOR SINGLE CELL TRAPPING

Yazarlar:

M.moghimi ZAND

Yayıncı:

Yildiz Technical University

Dergi:

Journal of Thermal Engineering 2017 Vol.3 Issue 4, pp.1319-1327

Belge Tipi:

Makale

Yayın Tarihi:

7/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000506386

Sıklık:

İki Aylık

eISSN:

2148-7847

DOI:

https://doi.org/10.18186/journal-of-thermal-engineering.330181

Özet:

 


Dielectrophoresis (DEP), as
a promising tool, have been used to separate, sort and deform bio-particles. In
traditional method of DEP, the direct contact of electrodes with bio-particles
leads to contamination and lysis of cells and joule heating in medium. In new
DEP methods, such as isolated DEP (iDEP) or contactless DEP (cDEP), some of
these rigors are overcame. In the method presented herein, these new techniques
are used to provide a non-uniform electric field to trap a single cell in a
desired area. We used the insulating structures to guide a flow as well as the
manipulation of particles. Finite element analysis (FEA) is used to obtain an
optimized microstructure. The joule heating and maximum DEP force is compared
with traditional method and results prove the capability of these systems to
trap a single cell efficiently.

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Makale detayları

DESIGN AND SIMULATION OF A NOVEL C-DEP MICROFLUIDICS FOR SINGLE CELL TRAPPING

Yazarlar: M.moghimi ZAND

Yayıncı: Yildiz Technical University

Dergi: Journal of Thermal Engineering 2017 Vol.3 Issue 4, pp.1319-1327

Belge Tipi: Makale

Yayın Tarihi: 7/2017

Belge Dili: Türkçe

Document ID (Org No.): 2000506386

Sıklık: İki Aylık

eISSN: 2148-7847

DOI: https://doi.org/10.18186/journal-of-thermal-engineering.330181

Sayı

Yazarlar:

M.moghimi ZAND

Yayıncı:

Yildiz Technical University

Dergi:

Journal of Thermal Engineering 2017 Vol.3 Issue 4, pp.1319-1327

Belge Tipi:

Makale

Yayın Tarihi:

7/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000506386

Sıklık:

İki Aylık

eISSN:

2148-7847

DOI:

https://doi.org/10.18186/journal-of-thermal-engineering.330181