The Effect of Cerebral White Matter Lesions on Walking Time & Vascular Risk Factors

Miray Erdem; Derya Ozdogru; Aygül Tantik Pak; Elif Banu Söker; Zülfikar Arlıer

Makale detayları

The Effect of Cerebral White Matter Lesions on Walking Time & Vascular Risk Factors

Yazarlar:

Miray Erdem | Derya Ozdogru | Aygül Tantik Pak | Elif Banu Söker | Zülfikar Arlıer

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık Kurumları Yönetimi | Tıp Eğitimi

Dergi:

Dicle Tıp Dergisi Vol.51 Issue 2, pp.191-198

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001319479

pISSN:

1300-2945

Anahtar kelimeler:

Özet:

 Introduction: White matter lesions are common neurological diseases in the elderly. In this study, we aimed to investigate the impact of cerebral white matter lesions on walking time and daily living activities in the elderly population. Methods: A total of 82 individuals, including 40 healthy volunteers and 42 age and sex-matched patients, were enrolled in this study. Magnetic resonance imaging findings were recorded based on the Fazekas Staging System. Risk factors potentially predisposing individuals to white matter lesions were documented through laboratory testing. Additionally, atherothrombotic plaque formations and stenosis were graded using Carotid and Vertebral Artery Doppler Ultrasonography in patients with white matter lesions. The Lawton Instrumental Activities of Daily Living Scale, Mini-Mental State Examination, and the Timed Up  Go Test were administered to both the patient and control groups to assess daily living activities and cognitive functions. Results: The results of this research showed that as the percentage of stenosis increased in Carotid and Vertebral Artery Doppler Ultrasonography, there were corresponding decreases in Lawton Instrumental Activities of Daily Living Scale scores, haemoglobin and hematocrit values while fasting blood glucose and homocysteine levels increased as expected. Furthermore, significant differences were observed in the Timed Up  Go Test in advanced stages when evaluated according to the Fazekas Staging System. Conclusion: Our study indicated that white matter lesions do not significantly affect daily living activities but prolong the walking time in elderly individuals.

 Introduction: White matter lesions are common neurological diseases in the elderly. In this study, we aimed to investigate the impact of cerebral white matter lesions on walking time and daily living activities in the elderly population. Methods: A total of 82 individuals, including 40 healthy volunteers and 42 age and sex-matched patients, were enrolled in this study. Magnetic resonance imaging findings were recorded based on the Fazekas Staging System. Risk factors potentially predisposing individuals to white matter lesions were documented through laboratory testing. Additionally, atherothrombotic plaque formations and stenosis were graded using Carotid and Vertebral Artery Doppler Ultrasonography in patients with white matter lesions. The Lawton Instrumental Activities of Daily Living Scale, Mini-Mental State Examination, and the Timed Up  Go Test were administered to both the patient and control groups to assess daily living activities and cognitive functions. Results: The results of this research showed that as the percentage of stenosis increased in Carotid and Vertebral Artery Doppler Ultrasonography, there were corresponding decreases in Lawton Instrumental Activities of Daily Living Scale scores, haemoglobin and hematocrit values while fasting blood glucose and homocysteine levels increased as expected. Furthermore, significant differences were observed in the Timed Up  Go Test in advanced stages when evaluated according to the Fazekas Staging System. Conclusion: Our study indicated that white matter lesions do not significantly affect daily living activities but prolong the walking time in elderly individuals.

 Introduction: White matter lesions are common neurological diseases in the elderly. In this study, we aimed to investigate the impact of cerebral white matter lesions on walking time and daily living activities in the elderly population. Methods: A total of 82 individuals, including 40 healthy volunteers and 42 age and sex-matched patients, were enrolled in this study. Magnetic resonance imaging findings were recorded based on the Fazekas Staging System. Risk factors potentially predisposing individuals to white matter lesions were documented through laboratory testing. Additionally, atherothrombotic plaque formations and stenosis were graded using Carotid and Vertebral Artery Doppler Ultrasonography in patients with white matter lesions. The Lawton Instrumental Activities of Daily Living Scale, Mini-Mental State Examination, and the Timed Up  Go Test were administered to both the patient and control groups to assess daily living activities and cognitive functions. Results: The results of this research showed that as the percentage of stenosis increased in Carotid and Vertebral Artery Doppler Ultrasonography, there were corresponding decreases in Lawton Instrumental Activities of Daily Living Scale scores, haemoglobin and hematocrit values while fasting blood glucose and homocysteine levels increased as expected. Furthermore, significant differences were observed in the Timed Up  Go Test in advanced stages when evaluated according to the Fazekas Staging System. Conclusion: Our study indicated that white matter lesions do not significantly affect daily living activities but prolong the walking time in elderly individuals.

 Introduction: White matter lesions are common neurological diseases in the elderly. In this study, we aimed to investigate the impact of cerebral white matter lesions on walking time and daily living activities in the elderly population. Methods: A total of 82 individuals, including 40 healthy volunteers and 42 age and sex-matched patients, were enrolled in this study. Magnetic resonance imaging findings were recorded based on the Fazekas Staging System. Risk factors potentially predisposing individuals to white matter lesions were documented through laboratory testing. Additionally, atherothrombotic plaque formations and stenosis were graded using Carotid and Vertebral Artery Doppler Ultrasonography in patients with white matter lesions. The Lawton Instrumental Activities of Daily Living Scale, Mini-Mental State Examination, and the Timed Up  Go Test were administered to both the patient and control groups to assess daily living activities and cognitive functions. Results: The results of this research showed that as the percentage of stenosis increased in Carotid and Vertebral Artery Doppler Ultrasonography, there were corresponding decreases in Lawton Instrumental Activities of Daily Living Scale scores, haemoglobin and hematocrit values while fasting blood glucose and homocysteine levels increased as expected. Furthermore, significant differences were observed in the Timed Up  Go Test in advanced stages when evaluated according to the Fazekas Staging System. Conclusion: Our study indicated that white matter lesions do not significantly affect daily living activities but prolong the walking time in elderly individuals.

Makale detayları

The Effect of Cerebral White Matter Lesions on Walking Time & Vascular Risk Factors

Yazarlar:

Miray Erdem | Derya Ozdogru | Aygül Tantik Pak | Elif Banu Söker | Zülfikar Arlıer

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık Kurumları Yönetimi | Tıp Eğitimi

Dergi:

Dicle Tıp Dergisi Vol.51 Issue 2, pp.191-198

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001319479

pISSN:

1300-2945

White Matter

Magnetic Resonance Imaging

Walking

Stroke

Brain

Gait

Sayı

Makale detayları

The Effect of Cerebral White Matter Lesions on Walking Time & Vascular Risk Factors

Yazarlar: Miray Erdem | Derya Ozdogru | Aygül Tantik Pak | Elif Banu Söker | Zülfikar Arlıer

Yayıncı: Dicle University

Ana Başlıklar: Sağlık Kurumları Yönetimi | Tıp Eğitimi

Dergi: Dicle Tıp Dergisi Vol.51 Issue 2, pp.191-198

Belge Tipi: Makale

Yayın Tarihi: 6/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001319479

pISSN: 1300-2945

White Matter

Magnetic Resonance Imaging

Walking

Stroke

Brain

Gait

Sayı

Yazarlar:

Miray Erdem | Derya Ozdogru | Aygül Tantik Pak | Elif Banu Söker | Zülfikar Arlıer

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık Kurumları Yönetimi | Tıp Eğitimi

Dergi:

Dicle Tıp Dergisi Vol.51 Issue 2, pp.191-198

Belge Tipi:

Makale

Yayın Tarihi:

6/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001319479

pISSN:

1300-2945