Antigenic Diversity of Bovine Viral Diarrhoea Viruses (BVDV) Isolated in Turkey

Kadir YEŞİLBAĞ; İbrahim BURGU

Makale detayları

Antigenic Diversity of Bovine Viral Diarrhoea Viruses (BVDV) Isolated in Turkey

Yazarlar:

Kadir YEŞİLBAĞ | İbrahim BURGU

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2006 Vol.30 Issue 6, pp.571-576

Belge Tipi:

Makale

Yayın Tarihi:

5/2006

Belge Dili:

Türkçe

Document ID (Org No.):

2000768330

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Anahtar kelimeler:

Özet:

 

Sixty BVDV field strains isolated from different regions of Turkey were antigenically characterised with a panel of 16 monoclonal antibodies (mAbs) specific to viral proteins E2 and NS2-3. MAb recognition patterns were detected by an indirect peroxidase-linked antibody assay and data were subjected to computer analysis for discussing herd specificity of viral strains isolated from immunotolerant, persistently infected (IPI) cattle. For that purpose, phylogenic and statistical analyses were performed. A high level of antigenic diversity was detected among the isolates. Diversity was also exhibited in IPI strains originating from the same herd. In some herds, viruses were divided into 2 viral subpopulations that were antigenically distinct from each other. The viruses in the subpopulations were significantly different from the viruses in the twin-subpopulation, as well as from viruses in other herds. This study demonstrated epitopic properties of Turkish BVDV field strains; yet, the results of this study do not support the concept of herd specificity of the virus.

 

Sixty BVDV field strains isolated from different regions of Turkey were antigenically characterised with a panel of 16 monoclonal antibodies (mAbs) specific to viral proteins E2 and NS2-3. MAb recognition patterns were detected by an indirect peroxidase-linked antibody assay and data were subjected to computer analysis for discussing herd specificity of viral strains isolated from immunotolerant, persistently infected (IPI) cattle. For that purpose, phylogenic and statistical analyses were performed. A high level of antigenic diversity was detected among the isolates. Diversity was also exhibited in IPI strains originating from the same herd. In some herds, viruses were divided into 2 viral subpopulations that were antigenically distinct from each other. The viruses in the subpopulations were significantly different from the viruses in the twin-subpopulation, as well as from viruses in other herds. This study demonstrated epitopic properties of Turkish BVDV field strains; yet, the results of this study do not support the concept of herd specificity of the virus.

Makale detayları

Antigenic Diversity of Bovine Viral Diarrhoea Viruses (BVDV) Isolated in Turkey

Yazarlar:

Kadir YEŞİLBAĞ | İbrahim BURGU

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2006 Vol.30 Issue 6, pp.571-576

Belge Tipi:

Makale

Yayın Tarihi:

5/2006

Belge Dili:

Türkçe

Document ID (Org No.):

2000768330

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Bovine viral diarrhoea

BVDV

monoclonal antibodies

antigenic diversity

phylogenetic analysis

herd specificity

Sayı

Makale detayları

Antigenic Diversity of Bovine Viral Diarrhoea Viruses (BVDV) Isolated in Turkey

Yazarlar: Kadir YEŞİLBAĞ | İbrahim BURGU

Yayıncı: TUBITAK

Dergi: Turkish Journal of Veterinary and Animal Sciences 2006 Vol.30 Issue 6, pp.571-576

Belge Tipi: Makale

Yayın Tarihi: 5/2006

Belge Dili: Türkçe

Document ID (Org No.): 2000768330

Sıklık: İki Aylık

eISSN: 1303-6181

pISSN: 1300-0128

Bovine viral diarrhoea

BVDV

monoclonal antibodies

antigenic diversity

phylogenetic analysis

herd specificity

Sayı

Yazarlar:

Kadir YEŞİLBAĞ | İbrahim BURGU

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2006 Vol.30 Issue 6, pp.571-576

Belge Tipi:

Makale

Yayın Tarihi:

5/2006

Belge Dili:

Türkçe

Document ID (Org No.):

2000768330

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128