The role of intravenous tranexamic acid for blood loss in total hip arthroplasty secondary to femoral neck fracture

Özgür Avci; Ali Şişman

Makale detayları

The role of intravenous tranexamic acid for blood loss in total hip arthroplasty secondary to femoral neck fracture

Yazarlar:

Özgür Avci | Ali Şişman

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 3, pp.630-634

Belge Tipi:

Makale

Yayın Tarihi:

5/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001290565

pISSN:

2636-8579

Anahtar kelimeler:

Özet:

 Aim: The aim of the study was to compare the efficacy of intravenous IV administration of tranexamic acid TXA in terms of bleeding volume, allogeneic blood transfusion ABT requirement, and complications in total hip arthroplasty THA secondary to osteoporotic femoral neck fracture FNF. Material and Method: A total of 165 patients who underwent THA on the background of FNF in our clinic were included in the study. Patients demographic data, preoperative and postoperative blood parameters, the amount of blood loss calculated according to the Nadler formula, amount of ABT, and complications at the 90-day follow-up were recorded. The patients were divided into two groups those who received 15mgkg preoperatively and 10mgkg IV TXA at the end of the operation TXA group-89 patients and those who did not receive TXA Control group-76 patients and the two groups were compared. Results: The total amount of bleeding calculated according to the Nadler formula was significantly less in the TXA group 1659,68320,86ml compared with the Control group 1774,43365,24ml p0.033. The need for ABT was 42.86 in the TXA group and 57.14 in the control group, and this difference was statistically significant p0.008. Conclusion: In patients who underwent THA on the basis of osteoporotic FNF, preoperative and postoperative administration of 2 doses of IV TXA significantly reduced total blood loss and the need for ABT. We suggest that IV TXA administration can be safely performed, especially in this patient group, to reduce the amount of bleeding and therefore the need for ABT by not increasing any thromboembolic complications.

 Aim: The aim of the study was to compare the efficacy of intravenous IV administration of tranexamic acid TXA in terms of bleeding volume, allogeneic blood transfusion ABT requirement, and complications in total hip arthroplasty THA secondary to osteoporotic femoral neck fracture FNF. Material and Method: A total of 165 patients who underwent THA on the background of FNF in our clinic were included in the study. Patients demographic data, preoperative and postoperative blood parameters, the amount of blood loss calculated according to the Nadler formula, amount of ABT, and complications at the 90-day follow-up were recorded. The patients were divided into two groups those who received 15mgkg preoperatively and 10mgkg IV TXA at the end of the operation TXA group-89 patients and those who did not receive TXA Control group-76 patients and the two groups were compared. Results: The total amount of bleeding calculated according to the Nadler formula was significantly less in the TXA group 1659,68320,86ml compared with the Control group 1774,43365,24ml p0.033. The need for ABT was 42.86 in the TXA group and 57.14 in the control group, and this difference was statistically significant p0.008. Conclusion: In patients who underwent THA on the basis of osteoporotic FNF, preoperative and postoperative administration of 2 doses of IV TXA significantly reduced total blood loss and the need for ABT. We suggest that IV TXA administration can be safely performed, especially in this patient group, to reduce the amount of bleeding and therefore the need for ABT by not increasing any thromboembolic complications.

 Aim: The aim of the study was to compare the efficacy of intravenous IV administration of tranexamic acid TXA in terms of bleeding volume, allogeneic blood transfusion ABT requirement, and complications in total hip arthroplasty THA secondary to osteoporotic femoral neck fracture FNF. Material and Method: A total of 165 patients who underwent THA on the background of FNF in our clinic were included in the study. Patients demographic data, preoperative and postoperative blood parameters, the amount of blood loss calculated according to the Nadler formula, amount of ABT, and complications at the 90-day follow-up were recorded. The patients were divided into two groups those who received 15mgkg preoperatively and 10mgkg IV TXA at the end of the operation TXA group-89 patients and those who did not receive TXA Control group-76 patients and the two groups were compared. Results: The total amount of bleeding calculated according to the Nadler formula was significantly less in the TXA group 1659,68320,86ml compared with the Control group 1774,43365,24ml p0.033. The need for ABT was 42.86 in the TXA group and 57.14 in the control group, and this difference was statistically significant p0.008. Conclusion: In patients who underwent THA on the basis of osteoporotic FNF, preoperative and postoperative administration of 2 doses of IV TXA significantly reduced total blood loss and the need for ABT. We suggest that IV TXA administration can be safely performed, especially in this patient group, to reduce the amount of bleeding and therefore the need for ABT by not increasing any thromboembolic complications.

 Aim: The aim of the study was to compare the efficacy of intravenous IV administration of tranexamic acid TXA in terms of bleeding volume, allogeneic blood transfusion ABT requirement, and complications in total hip arthroplasty THA secondary to osteoporotic femoral neck fracture FNF. Material and Method: A total of 165 patients who underwent THA on the background of FNF in our clinic were included in the study. Patients demographic data, preoperative and postoperative blood parameters, the amount of blood loss calculated according to the Nadler formula, amount of ABT, and complications at the 90-day follow-up were recorded. The patients were divided into two groups those who received 15mgkg preoperatively and 10mgkg IV TXA at the end of the operation TXA group-89 patients and those who did not receive TXA Control group-76 patients and the two groups were compared. Results: The total amount of bleeding calculated according to the Nadler formula was significantly less in the TXA group 1659,68320,86ml compared with the Control group 1774,43365,24ml p0.033. The need for ABT was 42.86 in the TXA group and 57.14 in the control group, and this difference was statistically significant p0.008. Conclusion: In patients who underwent THA on the basis of osteoporotic FNF, preoperative and postoperative administration of 2 doses of IV TXA significantly reduced total blood loss and the need for ABT. We suggest that IV TXA administration can be safely performed, especially in this patient group, to reduce the amount of bleeding and therefore the need for ABT by not increasing any thromboembolic complications.

Makale detayları

The role of intravenous tranexamic acid for blood loss in total hip arthroplasty secondary to femoral neck fracture

Yazarlar:

Özgür Avci | Ali Şişman

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 3, pp.630-634

Belge Tipi:

Makale

Yayın Tarihi:

5/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001290565

pISSN:

2636-8579

Total hip arthroplasty

tranexamic acid

blood loss

allogeneic blood transfusion

nadlerTotal hip arthroplasty

Tranexamic acid

Sayı

Makale detayları

The role of intravenous tranexamic acid for blood loss in total hip arthroplasty secondary to femoral neck fracture

Yazarlar: Özgür Avci | Ali Şişman

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Journal of Health Sciences and Medicine Vol.6 Issue 3, pp.630-634

Belge Tipi: Makale

Yayın Tarihi: 5/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001290565

pISSN: 2636-8579

Total hip arthroplasty

tranexamic acid

blood loss

allogeneic blood transfusion

nadlerTotal hip arthroplasty

Tranexamic acid

Sayı

Yazarlar:

Özgür Avci | Ali Şişman

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 3, pp.630-634

Belge Tipi:

Makale

Yayın Tarihi:

5/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001290565

pISSN:

2636-8579