A STUDY ON DIAGNOSTIC AND PROGNOSTIC ROLE OF PERIOSTIN IN RESPIRATORY SYSTEM DISEASE COMPLEX IN CALVES

Derviş Baran; İhsan Keleş

Makale detayları

A STUDY ON DIAGNOSTIC AND PROGNOSTIC ROLE OF PERIOSTIN IN RESPIRATORY SYSTEM DISEASE COMPLEX IN CALVES

Yazarlar:

Derviş Baran | İhsan Keleş

Yayıncı:

Erciyes University

Ana Başlıklar:

Veteriner Hekimlik

Dergi:

Sağlık Bilimleri Dergisi Vol.33 Issue 1, pp.25-34

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001315028

pISSN:

1018-3655

Anahtar kelimeler:

Özet:

 The purpose of this study was to compare the amounts of serum amyloid a, haptoglobin, fibrinogen, and periostin in calves with respiratory system disease complex before and after treatment. Three groups were used in the study: an acute group n10 made up of calves with acute respiratory system disease complex symptoms, a chronic group made up of calves with chronic respiratory system disease complex symptoms, and a control group made up of disease-free, healthy calves. Before and after therapy day 0, 7 and 14, clinical examinations were performed and blood samples were taken from the acute and chronic groups. Calves in the control group only had one clinical evaluation and blood sample collection. Results showed that both the acute and chronic groups exhibited clinical improvement after treatment. Before treatment, the concentrations of fibrinogen, serum amyloid A, and haptoglobin in the acute and chronic groups were significantly higher than those in the control group p0.001. On days 7 and 14, the serum periostin concentrations of the acute group were lower than those of the chronic group and control group p0.05. However, no significant difference was observed in serum periostin concentrations before and after treatment in both the acute and chronic groups p0.05. Additionally, a positive correlation was found between the respiratory system disease complex scores and the concentrations of serum amyloid A, haptoglobin, and fibrinogen. However, there was no significant correlation between periostin concentrations and respiratory system disease complex scores, as well as between fibrinogen, haptoglobin, and serum amyloid A concentrations p0.05.Based on the findings, it can be concluded that haptoglobin, serum amyloid A, and fibrinogen values, rather than periostin, play an important role in supporting the diagnosis and prognosis of respiratory system disease complex in calves.

 The purpose of this study was to compare the amounts of serum amyloid a, haptoglobin, fibrinogen, and periostin in calves with respiratory system disease complex before and after treatment. Three groups were used in the study: an acute group n10 made up of calves with acute respiratory system disease complex symptoms, a chronic group made up of calves with chronic respiratory system disease complex symptoms, and a control group made up of disease-free, healthy calves. Before and after therapy day 0, 7 and 14, clinical examinations were performed and blood samples were taken from the acute and chronic groups. Calves in the control group only had one clinical evaluation and blood sample collection. Results showed that both the acute and chronic groups exhibited clinical improvement after treatment. Before treatment, the concentrations of fibrinogen, serum amyloid A, and haptoglobin in the acute and chronic groups were significantly higher than those in the control group p0.001. On days 7 and 14, the serum periostin concentrations of the acute group were lower than those of the chronic group and control group p0.05. However, no significant difference was observed in serum periostin concentrations before and after treatment in both the acute and chronic groups p0.05. Additionally, a positive correlation was found between the respiratory system disease complex scores and the concentrations of serum amyloid A, haptoglobin, and fibrinogen. However, there was no significant correlation between periostin concentrations and respiratory system disease complex scores, as well as between fibrinogen, haptoglobin, and serum amyloid A concentrations p0.05.Based on the findings, it can be concluded that haptoglobin, serum amyloid A, and fibrinogen values, rather than periostin, play an important role in supporting the diagnosis and prognosis of respiratory system disease complex in calves.

 The purpose of this study was to compare the amounts of serum amyloid a, haptoglobin, fibrinogen, and periostin in calves with respiratory system disease complex before and after treatment. Three groups were used in the study: an acute group n10 made up of calves with acute respiratory system disease complex symptoms, a chronic group made up of calves with chronic respiratory system disease complex symptoms, and a control group made up of disease-free, healthy calves. Before and after therapy day 0, 7 and 14, clinical examinations were performed and blood samples were taken from the acute and chronic groups. Calves in the control group only had one clinical evaluation and blood sample collection. Results showed that both the acute and chronic groups exhibited clinical improvement after treatment. Before treatment, the concentrations of fibrinogen, serum amyloid A, and haptoglobin in the acute and chronic groups were significantly higher than those in the control group p0.001. On days 7 and 14, the serum periostin concentrations of the acute group were lower than those of the chronic group and control group p0.05. However, no significant difference was observed in serum periostin concentrations before and after treatment in both the acute and chronic groups p0.05. Additionally, a positive correlation was found between the respiratory system disease complex scores and the concentrations of serum amyloid A, haptoglobin, and fibrinogen. However, there was no significant correlation between periostin concentrations and respiratory system disease complex scores, as well as between fibrinogen, haptoglobin, and serum amyloid A concentrations p0.05.Based on the findings, it can be concluded that haptoglobin, serum amyloid A, and fibrinogen values, rather than periostin, play an important role in supporting the diagnosis and prognosis of respiratory system disease complex in calves.

 Bu çalışmada buzağılarda Solunum Sistemi Hastalıkları Kompleksin de serum amiloidA, haptoglobin, fibrinojen ve periostin konsantrasyonlarının tedavi öncesi ve tedavi sonrası değişimlerinin araştırılması amaçlandı. Çalışmada üç grup kullanılmıştır: Akut solunum sistemi hastalığı kompleksi semptomları olan buzağılardan oluşan bir akut grup n10, kronik solunum sistemi hastalığı kompleksi semptomları olan buzağılardan oluşan bir kronik grup ve hastalıksız, sağlıklı buzağılardan oluşan bir kontrol grubu. Tedaviden önce ve sonra 0, 7 ve 14. günler, akut ve kronik gruplardan klinik muayeneler yapıldı ve kan örnekleri alındı. Kontrol grubundaki buzağılardan sadece bir klinik değerlendirme ve kan örneği alınmıştır. Sonuçlar hem akut hem de kronik grupların tedaviden sonra klinik iyileşme gösterdiğini ortaya koymuştur. Tedavi öncesinde, akut ve kronik gruplardaki fibrinojen, serum amiloidA ve haptoglobin konsantrasyonları kontrol grubundakilerden anlamlı derecede yüksekti p0.001. 7. ve 14. günlerde, akut grubun serum periostin konsantrasyonları kronik grup ve kontrol grubundan daha düşüktü p0.05. Ancak, hem akut hem de kronik gruplarda tedavi öncesi ve sonrası serum periostin konsantrasyonlarında anlamlı bir fark gözlenmemiştir p0.05. Ayrıca, solunum sistemi hastalığı kompleksi skorları ile serum amiloidA, haptoglobinve fibrihojen konsantrasyonları arasında pozitif bir korelasyon bulunmuştur. Ancak, periostin konsantrasyonları ile solunum sistemi hastalığı kompleksi skorları arasında ve ayrıca fibrinojen, haptoglobin ve serum amiloidA konsantrasyonları arasında anlamlı bir korelasyon bulunmamıştır p0.05.Bulgulara dayanarak, buzağılarda solunum sistemi hastalığı kompleksinin tanı ve prognozunu desteklemede periostinden ziyade haptoglobin, serum amiloidA ve fibrinojen değerlerinin önemli bir rol oynadığı sonucuna varılabilir.

Makale detayları

A STUDY ON DIAGNOSTIC AND PROGNOSTIC ROLE OF PERIOSTIN IN RESPIRATORY SYSTEM DISEASE COMPLEX IN CALVES

Yazarlar:

Derviş Baran | İhsan Keleş

Yayıncı:

Erciyes University

Ana Başlıklar:

Veteriner Hekimlik

Dergi:

Sağlık Bilimleri Dergisi Vol.33 Issue 1, pp.25-34

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001315028

pISSN:

1018-3655

Calves

Diagnostic

Periostin

Prognostic

Respiratory systemBuzağı

Diagnostik

Periostin

Prognostik

Solunum Sistemi

Sayı

Makale detayları

Yazarlar: Derviş Baran | İhsan Keleş

Yayıncı: Erciyes University

Ana Başlıklar: Veteriner Hekimlik

Dergi: Sağlık Bilimleri Dergisi Vol.33 Issue 1, pp.25-34

Belge Tipi: Makale

Yayın Tarihi: 1/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001315028

pISSN: 1018-3655

Sayı

Yazarlar:

Derviş Baran | İhsan Keleş

Yayıncı:

Erciyes University

Ana Başlıklar:

Veteriner Hekimlik

Dergi:

Sağlık Bilimleri Dergisi Vol.33 Issue 1, pp.25-34

Belge Tipi:

Makale

Yayın Tarihi:

1/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001315028

pISSN:

1018-3655