Is ischemia modified albumin a good marker in acute exacerbation of chronic obstructive pulmonary disease?

Nalan OGAN; Togay EVRİN; Tuba ÇANDAR; Aslıhan ALHAN; Meral GÜLHAN

doi:https://doi.org/10.18621/eurj.517778

Makale detayları

Is ischemia modified albumin a good marker in acute exacerbation of chronic obstructive pulmonary disease?

Yazarlar:

Nalan OGAN | Togay EVRİN | Tuba ÇANDAR | Aslıhan ALHAN | Meral GÜLHAN

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Hastalıklar

Dergi:

The European Research Journal 2020 Vol.6 Issue 5, pp.388-394

Belge Tipi:

Makale

Yayın Tarihi:

9/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000662175

Sıklık:

İki Aylık

eISSN:

2149-3189

DOI:

https://doi.org/10.18621/eurj.517778

Özet:

 


Objectives:
Our
aim is to compare the Ischemia modified albumin (IMA) in patients with acute
exacerbation of Chronic Obstructive Pulmonary Disease (COPD) with a high
oxidative and inflammatory biologic marker like C-reactive protein (CRP) and to
investigate its employability in AECOPD and the relationship between arterial
blood gas and pulmonary function parameters. 


Methods: Forty-six
patients diagnosed with acute exacerbation of COPD between March 2015 -
September 2016 at Ufuk University School of Medicine were included. The 1st
and 5th days of IMA and CRP levels were measured. Also, IMA levels
were given in absorbance units (ABSU). 


Results: Total
46 patients of COPD, 13 (28.3%) were females and 33 (71.76%) were males. The
mean age of the patients was 71.39 ± 10.04 years. The 1st and 5th
day values of IMA, ABSU and CRP were 1.08 ± 0.33 and 0.49 ± 0.24; 1.06 ± 0.34
and 0.49 ± 0.26; and 29.25 (3.10-288.00) and 6.35 (0.30-149.00), respectively (p < 0.001). No significant
correlation was determined between IMA and CRP. Also, no correlation were
determined between the parameters of arterial blood gas and pulmonary function.










Conclusions: Although IMA values showed significant
increase during acute exacerbation of COPD and decreased after treatment, CRP
still appeared more effective in evaluating the exacerbation status and
following up of the treatment of patients with COPD. 



 


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Makale detayları

Is ischemia modified albumin a good marker in acute exacerbation of chronic obstructive pulmonary disease?

Yazarlar: Nalan OGAN | Togay EVRİN | Tuba ÇANDAR | Aslıhan ALHAN | Meral GÜLHAN

Yayıncı: Prusa Medical Publishing

Ana Başlıklar: Hastalıklar

Dergi: The European Research Journal 2020 Vol.6 Issue 5, pp.388-394

Belge Tipi: Makale

Yayın Tarihi: 9/2020

Belge Dili: İngilizce

Document ID (Org No.): 2000662175

Sıklık: İki Aylık

eISSN: 2149-3189

DOI: https://doi.org/10.18621/eurj.517778

Sayı

Yazarlar:

Nalan OGAN | Togay EVRİN | Tuba ÇANDAR | Aslıhan ALHAN | Meral GÜLHAN

Yayıncı:

Prusa Medical Publishing

Ana Başlıklar:

Hastalıklar

Dergi:

The European Research Journal 2020 Vol.6 Issue 5, pp.388-394

Belge Tipi:

Makale

Yayın Tarihi:

9/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000662175

Sıklık:

İki Aylık

eISSN:

2149-3189

DOI:

https://doi.org/10.18621/eurj.517778