A Rare Abnormal Male Karyotype with 46,X,DER(Y)(YQTER→P11.3::2Q2.1→QTER),DEL(2)(2PTER→11.3:)

Diclehan ORAL; Mahmut BALKAN; Selahattin TEKEŞ; İlyas YÜCEL; Gülbahar GÜZEL ERDAL; Mahir BİNİCİ; Fikriye Fulya KAVAK

Makale detayları

A Rare Abnormal Male Karyotype with 46,X,DER(Y)(YQTER→P11.3::2Q2.1→QTER),DEL(2)(2PTER→11.3:)

Yazarlar:

Diclehan ORAL | Mahmut BALKAN | Selahattin TEKEŞ | İlyas YÜCEL | Gülbahar GÜZEL ERDAL | Mahir BİNİCİ | Fikriye Fulya KAVAK

Yayıncı:

Veysi AKPOLAT

Ana Başlıklar:

Hastalıklar

Dergi:

International Archives of Medical Research 2021 Vol.13 Issue 1, pp.42-46

Belge Tipi:

Makale

Yayın Tarihi:

6/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000470210

Sıklık:

İki Yıllık

pISSN:

2146-6033

Özet:

 

Objective: Structural chromosomal abnormalities such as translocation in males and y deletions in the molecular missile cause infertility and related azoospermia. The aim of this study was to perform the karyotype analysis of a 51-year-old male patient who was referred to Dicle University Faculty of Medicine, Department of Medical Biology and Genetics for karyotype analysis due to primary infertility.
Methods: Chromosome analysis was performed in peripheral blood culture by applying the conventional cytogenetic method and GTG banding technique.
Results: Chromosome analysis a rare abnormal karyotype with 46, X, der(Y) (Yqter→p11.3::2q2.1→qter), del(2pte2q 11.3:) chromosomal structure was observed.  In thıs study, we report a case with a balanced translocation between chromosomes 2 and Y.
Conclusion: The causes leading to male infertility maybe later, and some of them are of genetic origin. While chromosomal abnormalities are seen in 0.5% of the healthy population, this rate increases to 5.8% in infertile men, so it is recommended to genetically investigate all individuals with azoospermia in semen analysis.

Makale detayları

A Rare Abnormal Male Karyotype with 46,X,DER(Y)(YQTER→P11.3::2Q2.1→QTER),DEL(2)(2PTER→11.3:)

Yazarlar: Diclehan ORAL | Mahmut BALKAN | Selahattin TEKEŞ | İlyas YÜCEL | Gülbahar GÜZEL ERDAL | Mahir BİNİCİ | Fikriye Fulya KAVAK

Yayıncı: Veysi AKPOLAT

Ana Başlıklar: Hastalıklar

Dergi: International Archives of Medical Research 2021 Vol.13 Issue 1, pp.42-46

Belge Tipi: Makale

Yayın Tarihi: 6/2021

Belge Dili: İngilizce

Document ID (Org No.): 2000470210

Sıklık: İki Yıllık

pISSN: 2146-6033

Sayı

Yazarlar:

Diclehan ORAL | Mahmut BALKAN | Selahattin TEKEŞ | İlyas YÜCEL | Gülbahar GÜZEL ERDAL | Mahir BİNİCİ | Fikriye Fulya KAVAK

Yayıncı:

Veysi AKPOLAT

Ana Başlıklar:

Hastalıklar

Dergi:

International Archives of Medical Research 2021 Vol.13 Issue 1, pp.42-46

Belge Tipi:

Makale

Yayın Tarihi:

6/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000470210

Sıklık:

İki Yıllık

pISSN:

2146-6033