A simple and efficient procedure for synthesis of optically active 1,3,4-oxadiazole derivatives containing L-amino acid moieties

Naser FOROUGHIFAR; Akbar Mobinikhaledi And Sattar EBRAHIMI; Sattar EBRAHIMI

Makale detayları

A simple and efficient procedure for synthesis of optically active 1,3,4-oxadiazole derivatives containing L-amino acid moieties

Yazarlar:

Naser FOROUGHIFAR | Akbar Mobinikhaledi And Sattar EBRAHIMI | Sattar EBRAHIMI

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2010 Vol.34 Issue 4, pp.603-611

Belge Tipi:

Makale

Yayın Tarihi:

3/2010

Belge Dili:

İngilizce

Document ID (Org No.):

2000728028

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

Some new unsymmetrical and optically active  2,5-disubstituted 1,3,4-oxadiazoles 5a-j were efficiently synthesized  by cyclization reaction of diacylhydrazides 4a-j.  The synthesis of  the title compounds was achieved by the reaction of acyl hydrazides  3a-b and N-phetaloyl-L-amino acids 1a-e in the presence of the  phosphoroxy chloride (POCl3) as an anhydrous reagent.

 

Some new unsymmetrical and optically active  2,5-disubstituted 1,3,4-oxadiazoles 5a-j were efficiently synthesized  by cyclization reaction of diacylhydrazides 4a-j.  The synthesis of  the title compounds was achieved by the reaction of acyl hydrazides  3a-b and N-phetaloyl-L-amino acids 1a-e in the presence of the  phosphoroxy chloride (POCl3) as an anhydrous reagent.

Makale detayları

A simple and efficient procedure for synthesis of optically active 1,3,4-oxadiazole derivatives containing L-amino acid moieties

Yazarlar: Naser FOROUGHIFAR | Akbar Mobinikhaledi And Sattar EBRAHIMI | Sattar EBRAHIMI

Yayıncı: TUBITAK

Ana Başlıklar: Uygulamalı fizik

Dergi: Turkish Journal of Chemistry 2010 Vol.34 Issue 4, pp.603-611

Belge Tipi: Makale

Yayın Tarihi: 3/2010

Belge Dili: İngilizce

Document ID (Org No.): 2000728028

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Naser FOROUGHIFAR | Akbar Mobinikhaledi And Sattar EBRAHIMI | Sattar EBRAHIMI

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2010 Vol.34 Issue 4, pp.603-611

Belge Tipi:

Makale

Yayın Tarihi:

3/2010

Belge Dili:

İngilizce

Document ID (Org No.):

2000728028

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527