Changes in Hemoglobin, Mean Thrombocid Volume and Neutrophil-Lymphocyte Ratio in Covıd-19 Infection

Adem Durmaz; Muammer Yılmaz

Makale detayları

Changes in Hemoglobin, Mean Thrombocid Volume and Neutrophil-Lymphocyte Ratio in Covıd-19 Infection

Yazarlar:

Adem Durmaz | Muammer Yılmaz

Yayıncı:

Sakarya University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Sakarya Üniversitesi Holistik Sağlık Dergisi Vol.6 Issue 1, pp.44-52

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001287038

pISSN:

2687-6078

Anahtar kelimeler:

Özet:

 Objective: It is aimed to evaluate the changes in blood and inflammatory markers Mean Platelet Volume and Neutrophil Lymphocyte Ratio in COVID-19. Method: We studied a total of 213 patients. 142 of them consist of patients who have undergone PCR test due to COVID-19 complaints and have a definite diagnosis. The blood values of 71 healthy people of similar age and characteristics without any complaints or symptoms were retrospectively compared. Results: The mean age of the COVID-19 group was 54.6217.71 years, while the COVID-19- group was 50.5415.74 years. 52.8 n:75 of the patient group and 54.9 n:39 of the COVID-19- group were women. There was a decrease in the number of platelets especially in the PCR group, but statistically no significant difference was observed between the PCR group and the COVID-19- group for hemoglobin and platelet values p0.05. However, a significant difference p 0.01 was found in Mean Platelet Volume, neutrophil, lymphocyte and Neutrophil Lymphocyte Ratio. Conclusion: Due to the cytokine storm that develops in COVID-19 infection, a number of changes occur in the blood, especially a decrease in thrombocyte counts. We think that especially the changes in Mean Platelet Volume and Neutrophil Lymphocyte Ratio, which are new inflammatory markers, can be used in the follow-up of this disease and its prognosis.

 Objective: It is aimed to evaluate the changes in blood and inflammatory markers Mean Platelet Volume and Neutrophil Lymphocyte Ratio in COVID-19. Method: We studied a total of 213 patients. 142 of them consist of patients who have undergone PCR test due to COVID-19 complaints and have a definite diagnosis. The blood values of 71 healthy people of similar age and characteristics without any complaints or symptoms were retrospectively compared. Results: The mean age of the COVID-19 group was 54.6217.71 years, while the COVID-19- group was 50.5415.74 years. 52.8 n:75 of the patient group and 54.9 n:39 of the COVID-19- group were women. There was a decrease in the number of platelets especially in the PCR group, but statistically no significant difference was observed between the PCR group and the COVID-19- group for hemoglobin and platelet values p0.05. However, a significant difference p 0.01 was found in Mean Platelet Volume, neutrophil, lymphocyte and Neutrophil Lymphocyte Ratio. Conclusion: Due to the cytokine storm that develops in COVID-19 infection, a number of changes occur in the blood, especially a decrease in thrombocyte counts. We think that especially the changes in Mean Platelet Volume and Neutrophil Lymphocyte Ratio, which are new inflammatory markers, can be used in the follow-up of this disease and its prognosis.

 Objective: It is aimed to evaluate the changes in blood and inflammatory markers Mean Platelet Volume and Neutrophil Lymphocyte Ratio in COVID-19. Method: We studied a total of 213 patients. 142 of them consist of patients who have undergone PCR test due to COVID-19 complaints and have a definite diagnosis. The blood values of 71 healthy people of similar age and characteristics without any complaints or symptoms were retrospectively compared. Results: The mean age of the COVID-19 group was 54.6217.71 years, while the COVID-19- group was 50.5415.74 years. 52.8 n:75 of the patient group and 54.9 n:39 of the COVID-19- group were women. There was a decrease in the number of platelets especially in the PCR group, but statistically no significant difference was observed between the PCR group and the COVID-19- group for hemoglobin and platelet values p0.05. However, a significant difference p 0.01 was found in Mean Platelet Volume, neutrophil, lymphocyte and Neutrophil Lymphocyte Ratio. Conclusion: Due to the cytokine storm that develops in COVID-19 infection, a number of changes occur in the blood, especially a decrease in thrombocyte counts. We think that especially the changes in Mean Platelet Volume and Neutrophil Lymphocyte Ratio, which are new inflammatory markers, can be used in the follow-up of this disease and its prognosis.

 Amaç: Dünya genelinde büyük bir salgın yapan COVID-19 hastalığında, kanda ve inflamatuvar belirteçlerde Ortalama Trombosit Hacmi ve Nötrofil Lenfosit Oranı meydana gelen değişimleri değerlendirmek amaçlanmıştır. Yöntem: Çalışma, toplam 213 kişi ile yapılmıştır. Bunların 142 kişisi COVID-19 şikâyetleri nedeniyle Real Time Polimeraz Zincir Reaksiyonu PCR testi yapılmış ve kesin tanısı konmuş hastalardan oluşmaktadır. Benzer yaş ve özellikte hiçbir şikayet ve semptomu olmayan 71 adet sağlıklı insanın kan değerleri ile retrospektif olarak karşılaştırılmıştır. Bulgular: COVID-19 pozitif grubun yaş ortalaması 54.6217.71 yıl iken kontrol grubunun 50.5415.74 yıl idi. Hasta grubunun 52,8si n:75 kontrol grubunun ise 54,9u n:39 kadınlardan oluşmaktaydı. Özellikle PCR pozitif grupta platelet sayılarında düşüş saptanmıştır ama istatiksel açıdan PCR pozitif grup ile kontrol grubu arasında hemoglobin ve platelet değerleri için anlamlı bir farklılık gözlenmemiştir p0,05. Ama Ortalama Trombosit Hacmi, nötrofil, lenfosit ve nötrofil lenfosit oranlarında anlamlı farklılık p0,01 saptanmıştır. Sonuç: COVID-19 enfeksiyonunda gelişen sitokin fırtınası nedeniyle kanda trombosit sayılarında azalma başta olmak üzere bir dizi değişiklikler meydana gelmektedir. Özellikle yeni inflamatuvar markerlerdan olan Ortalama Trombosit Hacmi ve Nötrofil Lenfosit Oranında meydana gelen değişiklikler bu hastalığın ve prognozunun takibinde kullanılabileceğini düşünmekteyiz.

Makale detayları

Changes in Hemoglobin, Mean Thrombocid Volume and Neutrophil-Lymphocyte Ratio in Covıd-19 Infection

Yazarlar:

Adem Durmaz | Muammer Yılmaz

Yayıncı:

Sakarya University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Sakarya Üniversitesi Holistik Sağlık Dergisi Vol.6 Issue 1, pp.44-52

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001287038

pISSN:

2687-6078

COVID-19

hemoglobin

platelet

neutrophil

lymphocyte

Covid 19

hemoglobin

trombosit

nötrofil

lenfosit

Sayı

Makale detayları

Yazarlar: Adem Durmaz | Muammer Yılmaz

Yayıncı: Sakarya University

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Sakarya Üniversitesi Holistik Sağlık Dergisi Vol.6 Issue 1, pp.44-52

Belge Tipi: Makale

Yayın Tarihi: 4/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001287038

pISSN: 2687-6078

Sayı

Yazarlar:

Adem Durmaz | Muammer Yılmaz

Yayıncı:

Sakarya University

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Sakarya Üniversitesi Holistik Sağlık Dergisi Vol.6 Issue 1, pp.44-52

Belge Tipi:

Makale

Yayın Tarihi:

4/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001287038

pISSN:

2687-6078