Hüseyin Eray BULUT,  Erdoğan GÜRSOY

Hüseyin Eray BULUT

Makale detayları

Hüseyin Eray BULUT, Erdoğan GÜRSOY

Yazarlar:

Hüseyin Eray BULUT

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1998 Vol.28 Issue 2, pp.123-126

Belge Tipi:

Makale

Yayın Tarihi:

1/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000758423

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

Cryptorchidism causes a failure in  testosterone secretion from the testicles. The  metabolism of the adrenocortical steroids is  influenced by sex hormones. Therefore testicular  failure may cause structural and func-tional  alterations in adrenal cortex. It is the  aim of the present study to evaluate the effect  of experimental caryptorchidism on the  ultrastructure of the rat adrenal cortex, especialy  on the reticularis region during prepubertal  and postpubertal ages.  Three groups of animals were used in the  present study. The first (prepubertal) group  consisted of 5,21-day old rats whereas the  second (postpubertal) group was made of  5,3-month old rats. Third group was the control  group which had 5,6-month old normal  animals. Testicles from each animal in experimental  groups were pulled into the peritoneal  cavity and fixed on the peritoneal wall. Following  a 3 month period, all animals were  killed and the adrenal glands were obtained  from each animal. Adrenal cortical tissue  were processed for electron microscopy, and  the ultrastructure of zona reticularis cells was  evaluated using a JEOL 100C electron microscope.  In the prepubertal group, hypertrophic  smooth endoplasmic reticulum (SER), a dramatic  increase in tubular type mitochondrial  size, and the number and size of the lipid  droplets in reticularis cells were major findings  of the present study. On the other hand,  cellular structures of the rat adrenal cortex in  the postpubertal group were similar to those  seen in the control group.  These findings suggested a more changed cellular  structure under the influence of experimental  cryptorchidism in rats during prepubertal  age. However, experimental  cryptorchidism had no effect when performed  in the postpubertal age.

 

Cryptorchidism causes a failure in  testosterone secretion from the testicles. The  metabolism of the adrenocortical steroids is  influenced by sex hormones. Therefore testicular  failure may cause structural and func-tional  alterations in adrenal cortex. It is the  aim of the present study to evaluate the effect  of experimental caryptorchidism on the  ultrastructure of the rat adrenal cortex, especialy  on the reticularis region during prepubertal  and postpubertal ages.  Three groups of animals were used in the  present study. The first (prepubertal) group  consisted of 5,21-day old rats whereas the  second (postpubertal) group was made of  5,3-month old rats. Third group was the control  group which had 5,6-month old normal  animals. Testicles from each animal in experimental  groups were pulled into the peritoneal  cavity and fixed on the peritoneal wall. Following  a 3 month period, all animals were  killed and the adrenal glands were obtained  from each animal. Adrenal cortical tissue  were processed for electron microscopy, and  the ultrastructure of zona reticularis cells was  evaluated using a JEOL 100C electron microscope.  In the prepubertal group, hypertrophic  smooth endoplasmic reticulum (SER), a dramatic  increase in tubular type mitochondrial  size, and the number and size of the lipid  droplets in reticularis cells were major findings  of the present study. On the other hand,  cellular structures of the rat adrenal cortex in  the postpubertal group were similar to those  seen in the control group.  These findings suggested a more changed cellular  structure under the influence of experimental  cryptorchidism in rats during prepubertal  age. However, experimental  cryptorchidism had no effect when performed  in the postpubertal age.

Makale detayları

Hüseyin Eray BULUT, Erdoğan GÜRSOY

Yazarlar: Hüseyin Eray BULUT

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 1998 Vol.28 Issue 2, pp.123-126

Belge Tipi: Makale

Yayın Tarihi: 1/1998

Belge Dili: Türkçe

Document ID (Org No.): 2000758423

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Cryptorchidism

adrenal cortex

ultrastructure

Sayı

Yazarlar:

Hüseyin Eray BULUT

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1998 Vol.28 Issue 2, pp.123-126

Belge Tipi:

Makale

Yayın Tarihi:

1/1998

Belge Dili:

Türkçe

Document ID (Org No.):

2000758423

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144