N -functionalized benzimidazol-2-ylidene silver complexes: synthesis, characterization, and antimicrobial studies

Yetkin GÖK; Senem AKKOÇ; Özlem Özeroğlu ÇELİKAL; İlknur ÖZDEMİR; Selami GÜNAL; Elif SAYIN

doi:https://doi.org/10.3906/kim-1304-72

Makale detayları

N -functionalized benzimidazol-2-ylidene silver complexes: synthesis, characterization, and antimicrobial studies

Yazarlar:

Yetkin GÖK | Senem AKKOÇ | Özlem Özeroğlu ÇELİKAL | İlknur ÖZDEMİR | Selami GÜNAL | Elif SAYIN

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2013 Vol.37 Issue 6, pp.1007-1013

Belge Tipi:

Makale

Yayın Tarihi:

5/2013

Belge Dili:

İngilizce

Document ID (Org No.):

2000727313

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

DOI:

https://doi.org/10.3906/kim-1304-72

Özet:

 

2-Methoxyethyl, 2-diethylaminoethyl, and  2-phenylethyl-substituted N-heterocyclic carbene (NHC) precursors were  treated with Ag2CO3 to yield silver(I)-NHC complexes  (1a--g) in dichloromethane as a solvent at room temperature. The 7  new silver-NHC complexes were fully characterized by means of 1H NMR,  13C NMR, and elemental analysis techniques. Using the agar dilution  procedure recommended by the Laboratory and Clinical Standards Institute,  the antimicrobial activities of all the silver-NHC complexes were studied  against 2 gram-negative bacterial strains (Pseudomonas aeruginosa and Escherichia coli), 2 gram-positive bacterial  strains (Enterococcus faecalis and Staphylococcus aureus), and 2 fungi (Candida tropicalis and Candida albicans).

 

2-Methoxyethyl, 2-diethylaminoethyl, and  2-phenylethyl-substituted N-heterocyclic carbene (NHC) precursors were  treated with Ag2CO3 to yield silver(I)-NHC complexes  (1a--g) in dichloromethane as a solvent at room temperature. The 7  new silver-NHC complexes were fully characterized by means of 1H NMR,  13C NMR, and elemental analysis techniques. Using the agar dilution  procedure recommended by the Laboratory and Clinical Standards Institute,  the antimicrobial activities of all the silver-NHC complexes were studied  against 2 gram-negative bacterial strains (Pseudomonas aeruginosa and Escherichia coli), 2 gram-positive bacterial  strains (Enterococcus faecalis and Staphylococcus aureus), and 2 fungi (Candida tropicalis and Candida albicans).

Makale detayları

N -functionalized benzimidazol-2-ylidene silver complexes: synthesis, characterization, and antimicrobial studies

Yazarlar: Yetkin GÖK | Senem AKKOÇ | Özlem Özeroğlu ÇELİKAL | İlknur ÖZDEMİR | Selami GÜNAL | Elif SAYIN

Yayıncı: TUBITAK

Ana Başlıklar: Uygulamalı fizik

Dergi: Turkish Journal of Chemistry 2013 Vol.37 Issue 6, pp.1007-1013

Belge Tipi: Makale

Yayın Tarihi: 5/2013

Belge Dili: İngilizce

Document ID (Org No.): 2000727313

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

DOI: https://doi.org/10.3906/kim-1304-72

Sayı

Yazarlar:

Yetkin GÖK | Senem AKKOÇ | Özlem Özeroğlu ÇELİKAL | İlknur ÖZDEMİR | Selami GÜNAL | Elif SAYIN

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2013 Vol.37 Issue 6, pp.1007-1013

Belge Tipi:

Makale

Yayın Tarihi:

5/2013

Belge Dili:

İngilizce

Document ID (Org No.):

2000727313

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

DOI:

https://doi.org/10.3906/kim-1304-72