Eosinophils in lung tissue in 2 Chilean Criollo horses with exacerbated recurrent airway obstructions “heaves”

Alexander ORTLOFF; Hugo FOLCH; Gabriel MORÁN

Makale detayları

Eosinophils in lung tissue in 2 Chilean Criollo horses with exacerbated recurrent airway obstructions “heaves”

Yazarlar:

Alexander ORTLOFF | Hugo FOLCH | Gabriel MORÁN

Yayıncı:

TUBITAK

Ana Başlıklar:

Hayvancılık

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2011 Vol.35 Issue 2, pp.93-97

Belge Tipi:

Makale

Yayın Tarihi:

1/2011

Belge Dili:

İngilizce

Document ID (Org No.):

2000767242

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Anahtar kelimeler:

Özet:

 

We report on 2 cases of recurrent airway obstruction (RAO) observed in Chilean Criollo horses aged 13 and 15 years. Both animals were classified as having severe RAO. The analysis of the recovered cells of bronchoalveolar lavage fluid (BALF) showed high percentages of eosinophils (82% and 80% in the differential cell counts of the 2 horses) and poor responses to bronchodilator and corticosteroid drugs. The histopathological lung evaluation showed eosinophilic infiltration in the peribronchial tissue, as well as in the lumen of the bronchi and bronchioli. In both horses, immunohistochemistry confirmed high p65 homodimer activity in bronchial cells. This report describes exacerbated heaves with eosinophilic infiltration and p65 activity in the lung tissue without any neutrophil infiltration, which is usually characteristic for this disease.

 

We report on 2 cases of recurrent airway obstruction (RAO) observed in Chilean Criollo horses aged 13 and 15 years. Both animals were classified as having severe RAO. The analysis of the recovered cells of bronchoalveolar lavage fluid (BALF) showed high percentages of eosinophils (82% and 80% in the differential cell counts of the 2 horses) and poor responses to bronchodilator and corticosteroid drugs. The histopathological lung evaluation showed eosinophilic infiltration in the peribronchial tissue, as well as in the lumen of the bronchi and bronchioli. In both horses, immunohistochemistry confirmed high p65 homodimer activity in bronchial cells. This report describes exacerbated heaves with eosinophilic infiltration and p65 activity in the lung tissue without any neutrophil infiltration, which is usually characteristic for this disease.

Makale detayları

Eosinophils in lung tissue in 2 Chilean Criollo horses with exacerbated recurrent airway obstructions “heaves”

Yazarlar:

Alexander ORTLOFF | Hugo FOLCH | Gabriel MORÁN

Yayıncı:

TUBITAK

Ana Başlıklar:

Hayvancılık

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2011 Vol.35 Issue 2, pp.93-97

Belge Tipi:

Makale

Yayın Tarihi:

1/2011

Belge Dili:

İngilizce

Document ID (Org No.):

2000767242

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

eosinophils

p65 homodimers

Chilean Criollo horses

Heaves

Sayı

Makale detayları

Eosinophils in lung tissue in 2 Chilean Criollo horses with exacerbated recurrent airway obstructions “heaves”

Yazarlar: Alexander ORTLOFF | Hugo FOLCH | Gabriel MORÁN

Yayıncı: TUBITAK

Ana Başlıklar: Hayvancılık

Dergi: Turkish Journal of Veterinary and Animal Sciences 2011 Vol.35 Issue 2, pp.93-97

Belge Tipi: Makale

Yayın Tarihi: 1/2011

Belge Dili: İngilizce

Document ID (Org No.): 2000767242

Sıklık: İki Aylık

eISSN: 1303-6181

pISSN: 1300-0128

eosinophils

p65 homodimers

Chilean Criollo horses

Heaves

Sayı

Yazarlar:

Alexander ORTLOFF | Hugo FOLCH | Gabriel MORÁN

Yayıncı:

TUBITAK

Ana Başlıklar:

Hayvancılık

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2011 Vol.35 Issue 2, pp.93-97

Belge Tipi:

Makale

Yayın Tarihi:

1/2011

Belge Dili:

İngilizce

Document ID (Org No.):

2000767242

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128