Analysis of clinical findings and serum micronutrients in pediatric patients with nonalcoholic fatty liver disease

Meryem Keçeli Başaran; Okan Gürkan

Makale detayları

Analysis of clinical findings and serum micronutrients in pediatric patients with nonalcoholic fatty liver disease

Yazarlar:

Meryem Keçeli Başaran | Okan Gürkan

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 1, pp.35-39

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282281

pISSN:

2636-8579

Anahtar kelimeler:

Özet:

 Aim: Nonalcoholic fatty liver disease NAFLD is the hepatic finding of systemic lipid and energy metabolism disorder. NAFLD is frequently observed in people with higher body mass index. Serum micronutrient levels play an important role in hepatic metabolism. Material and Method: This study included 60 NAFLD and 66 control patients. . NAFLD and control groups were compared in terms of ultrasonography USG and shear wave elastography SWE results. The two groups were compared in serum lipid profile, aminotransferase, insulin, glucose, and HOMA-IR. Both groups were then analyzed in terms of serum ferritin, B12, and vitamin D levels. Results: . 35 n21 of the patients in the NAFLD group had grade 1, 55 n33 had grade 2 and 10 n6 had grade 3 adiposity. HOMA-IR and insulin levels were higher in the NAFLD group p0.02; p0.001. While the serum ferritin level of the patients in the NAFLD group was higher than the control group p0.001; the B12 level was lower p0.006. In terms of vitamin D, there was no difference p0.368. Conclusion: It is essential to identify risk factors in children on follow-up due to NAFLD. USG and liver function tests remain the first option in the diagnosis and screening of NAFLD in children. Serum ferritin, B12, and vitamin D levels of children on follow-up due to NAFLD should be analyzed in consideration of liver fattening.

 Aim: Nonalcoholic fatty liver disease NAFLD is the hepatic finding of systemic lipid and energy metabolism disorder. NAFLD is frequently observed in people with higher body mass index. Serum micronutrient levels play an important role in hepatic metabolism. Material and Method: This study included 60 NAFLD and 66 control patients. . NAFLD and control groups were compared in terms of ultrasonography USG and shear wave elastography SWE results. The two groups were compared in serum lipid profile, aminotransferase, insulin, glucose, and HOMA-IR. Both groups were then analyzed in terms of serum ferritin, B12, and vitamin D levels. Results: . 35 n21 of the patients in the NAFLD group had grade 1, 55 n33 had grade 2 and 10 n6 had grade 3 adiposity. HOMA-IR and insulin levels were higher in the NAFLD group p0.02; p0.001. While the serum ferritin level of the patients in the NAFLD group was higher than the control group p0.001; the B12 level was lower p0.006. In terms of vitamin D, there was no difference p0.368. Conclusion: It is essential to identify risk factors in children on follow-up due to NAFLD. USG and liver function tests remain the first option in the diagnosis and screening of NAFLD in children. Serum ferritin, B12, and vitamin D levels of children on follow-up due to NAFLD should be analyzed in consideration of liver fattening.

 Aim: Nonalcoholic fatty liver disease NAFLD is the hepatic finding of systemic lipid and energy metabolism disorder. NAFLD is frequently observed in people with higher body mass index. Serum micronutrient levels play an important role in hepatic metabolism. Material and Method: This study included 60 NAFLD and 66 control patients. . NAFLD and control groups were compared in terms of ultrasonography USG and shear wave elastography SWE results. The two groups were compared in serum lipid profile, aminotransferase, insulin, glucose, and HOMA-IR. Both groups were then analyzed in terms of serum ferritin, B12, and vitamin D levels. Results: . 35 n21 of the patients in the NAFLD group had grade 1, 55 n33 had grade 2 and 10 n6 had grade 3 adiposity. HOMA-IR and insulin levels were higher in the NAFLD group p0.02; p0.001. While the serum ferritin level of the patients in the NAFLD group was higher than the control group p0.001; the B12 level was lower p0.006. In terms of vitamin D, there was no difference p0.368. Conclusion: It is essential to identify risk factors in children on follow-up due to NAFLD. USG and liver function tests remain the first option in the diagnosis and screening of NAFLD in children. Serum ferritin, B12, and vitamin D levels of children on follow-up due to NAFLD should be analyzed in consideration of liver fattening.

 Aim: Nonalcoholic fatty liver disease NAFLD is the hepatic finding of systemic lipid and energy metabolism disorder. NAFLD is frequently observed in people with higher body mass index. Serum micronutrient levels play an important role in hepatic metabolism. Material and Method: This study included 60 NAFLD and 66 control patients. . NAFLD and control groups were compared in terms of ultrasonography USG and shear wave elastography SWE results. The two groups were compared in serum lipid profile, aminotransferase, insulin, glucose, and HOMA-IR. Both groups were then analyzed in terms of serum ferritin, B12, and vitamin D levels. Results: . 35 n21 of the patients in the NAFLD group had grade 1, 55 n33 had grade 2 and 10 n6 had grade 3 adiposity. HOMA-IR and insulin levels were higher in the NAFLD group p0.02; p0.001. While the serum ferritin level of the patients in the NAFLD group was higher than the control group p0.001; the B12 level was lower p0.006. In terms of vitamin D, there was no difference p0.368. Conclusion: It is essential to identify risk factors in children on follow-up due to NAFLD. USG and liver function tests remain the first option in the diagnosis and screening of NAFLD in children. Serum ferritin, B12, and vitamin D levels of children on follow-up due to NAFLD should be analyzed in consideration of liver fattening.

Makale detayları

Analysis of clinical findings and serum micronutrients in pediatric patients with nonalcoholic fatty liver disease

Yazarlar:

Meryem Keçeli Başaran | Okan Gürkan

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 1, pp.35-39

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282281

pISSN:

2636-8579

Fatty liver

vitamin

ferritin

elastography

Fatty liver

vitamin

ferritin

elastography

Sayı

Makale detayları

Yazarlar: Meryem Keçeli Başaran | Okan Gürkan

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: Sağlık Kurumları Yönetimi

Dergi: Journal of Health Sciences and Medicine Vol.6 Issue 1, pp.35-39

Belge Tipi: Makale

Yayın Tarihi: 12/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001282281

pISSN: 2636-8579

Sayı

Yazarlar:

Meryem Keçeli Başaran | Okan Gürkan

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Sağlık Kurumları Yönetimi

Dergi:

Journal of Health Sciences and Medicine Vol.6 Issue 1, pp.35-39

Belge Tipi:

Makale

Yayın Tarihi:

12/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001282281

pISSN:

2636-8579