Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils

Gülmira Özek

doi:https://doi.org/10.18596/jotcsa.389075

Makale detayları

Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils

Yazarlar:

Gülmira Özek

Yayıncı:

Turkish Chemical Society

Ana Başlıklar:

Kimya mühendisliği

Dergi:

Journal of the Turkish Chemical Society Section A: Chemistry 2018 Vol.5 Issue 2, pp.493-510

Belge Tipi:

Makale

Yayın Tarihi:

12/2017

Belge Dili:

İngilizce

Document ID (Org No.):

2000503151

Sıklık:

Üç Aylık

eISSN:

2149-0120

DOI:

https://doi.org/10.18596/jotcsa.389075

Özet:

 


Two samples of Tanacetum
praeteritum (Horwood) Heywood subsp. praeteritum
(Horwood) were collected in flowering period and subjected separately to
hydrodistillation to yield the essential oils (A and B). The oils were
investigated for chemical composition with GC-FID and GC/MS techniques and
evaluated against acetylcholinesterase and a-amylase enzymes and
free radicals (DPPH• and ABTS•+) using microtiter plate
assays. Both of the oils were characterized with high abundance of oxygenated
monoterpenes. The oils were distinguished by the main constituents, namely,
camphor (37.6 %), 1,8-cineole (19.5 %) and terpinen-4-ol (9.3 %) were found as
the major constituents in the oil A, while a-thujone (79.4 %) and
b-thujone
(8.5 %) were detected in the oil B. The oils demonstrated significant
inhibitory (80 % and 60.0 %) potentials on acetylcholinesterase (an IC50
of 0.74 mg/mL and an IC50 of 1.78 mg/mL, respectively) which
involved into Alzheimer’s disease. With respect to antidiabetic activity, the
oils demonstrated significant inhibiting potential on porcine pancreatic a-amylase
(an IC50 of 1.02 mg/mL and an IC50 of 0.89 mg/mL) in I2/KI
assay. The oils demonstrated weak free radical scavenging activity against DPPH
radicals and moderate activity (0.23 mM and 0.15 mM) against ABTS+•
in TEAC assay. 




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Makale detayları

Chemical Diversity and Biological Potential of Tanacetum praeteritum subsp. praeteritum Essential Oils

Yazarlar: Gülmira Özek

Yayıncı: Turkish Chemical Society

Ana Başlıklar: Kimya mühendisliği

Dergi: Journal of the Turkish Chemical Society Section A: Chemistry 2018 Vol.5 Issue 2, pp.493-510

Belge Tipi: Makale

Yayın Tarihi: 12/2017

Belge Dili: İngilizce

Document ID (Org No.): 2000503151

Sıklık: Üç Aylık

eISSN: 2149-0120

DOI: https://doi.org/10.18596/jotcsa.389075

Sayı

Yazarlar:

Gülmira Özek

Yayıncı:

Turkish Chemical Society

Ana Başlıklar:

Kimya mühendisliği

Dergi:

Journal of the Turkish Chemical Society Section A: Chemistry 2018 Vol.5 Issue 2, pp.493-510

Belge Tipi:

Makale

Yayın Tarihi:

12/2017

Belge Dili:

İngilizce

Document ID (Org No.):

2000503151

Sıklık:

Üç Aylık

eISSN:

2149-0120

DOI:

https://doi.org/10.18596/jotcsa.389075