Comparison of Hybrid Techniques with 3D-Conformal Radiotherapy in Patients with Lung Cancer

Ömer Azaklıoğlu; Doğukan Akçay; İlhami Er; Kadir Akgüngör; Ayşe Nur Demiral

Makale detayları

Comparison of Hybrid Techniques with 3D-Conformal Radiotherapy in Patients with Lung Cancer

Yazarlar:

Ömer Azaklıoğlu | Doğukan Akçay | İlhami Er | Kadir Akgüngör | Ayşe Nur Demiral

Yayıncı:

Dokuz Eylul University

Ana Başlıklar:

Health Care Administration

Dergi:

Journal of Basic and Clinical Health Sciences Vol.7 Issue 3, pp.50-57

Belge Tipi:

Makale

Yayın Tarihi:

9/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001299969

pISSN:

2564-7288

Anahtar kelimeler:

Özet:

 Purpose: Its postulated that hybrid techniques HT with lower weighting of IMRTVMAT component would improve lung dose-volume parameters despite some disadvantage in PTV homogeneity index HI and target coverage TC. Material and Methods: Conformal plans were prepared using 6-10-15 MV-X photon energies while IMRTVMAT plans of HTs were prepared using 6MV-X. Four HTs were developed having two different ratios 10 and 50 of IMRTVMAT component h-IMRT1, h-IMRT2 and h-VMAT1, h-VMAT2, respectively. HTs were compared with 3D-CRT in terms of HI and TC for PTV, and total lung TL and contralateral lung CL V5Gy, V10Gy, V20Gy and mean lung dose MLD. Results: All HTs were advantageous for HI and TC, while disadvantageous for TL and CL-V5Gy. H-IMRT2 provided better TC than h-IMRT1, and so did h-VMAT2 compared to h-VMAT1. Lower weighting of IMRTVMAT decreased TL and CL-V5Gy in HTs. In addition, h-IMRT1 decreased TL and CL-MLD and CL-V20Gy compared to h-IMRT2, while h-VMAT2 decreased TL-V20Gy and CL-MLD compared to h-VMAT2. Conclusion: In the RT of lung tumors close to vertebra, it may be appropriate to suggest a ratio of IMRTVMAT component about 10 in order to decrease the low and intermediate dose-wash lung volume, if HI and TC values are acceptable.

 Purpose: Its postulated that hybrid techniques HT with lower weighting of IMRTVMAT component would improve lung dose-volume parameters despite some disadvantage in PTV homogeneity index HI and target coverage TC. Material and Methods: Conformal plans were prepared using 6-10-15 MV-X photon energies while IMRTVMAT plans of HTs were prepared using 6MV-X. Four HTs were developed having two different ratios 10 and 50 of IMRTVMAT component h-IMRT1, h-IMRT2 and h-VMAT1, h-VMAT2, respectively. HTs were compared with 3D-CRT in terms of HI and TC for PTV, and total lung TL and contralateral lung CL V5Gy, V10Gy, V20Gy and mean lung dose MLD. Results: All HTs were advantageous for HI and TC, while disadvantageous for TL and CL-V5Gy. H-IMRT2 provided better TC than h-IMRT1, and so did h-VMAT2 compared to h-VMAT1. Lower weighting of IMRTVMAT decreased TL and CL-V5Gy in HTs. In addition, h-IMRT1 decreased TL and CL-MLD and CL-V20Gy compared to h-IMRT2, while h-VMAT2 decreased TL-V20Gy and CL-MLD compared to h-VMAT2. Conclusion: In the RT of lung tumors close to vertebra, it may be appropriate to suggest a ratio of IMRTVMAT component about 10 in order to decrease the low and intermediate dose-wash lung volume, if HI and TC values are acceptable.

 Purpose: Its postulated that hybrid techniques HT with lower weighting of IMRTVMAT component would improve lung dose-volume parameters despite some disadvantage in PTV homogeneity index HI and target coverage TC. Material and Methods: Conformal plans were prepared using 6-10-15 MV-X photon energies while IMRTVMAT plans of HTs were prepared using 6MV-X. Four HTs were developed having two different ratios 10 and 50 of IMRTVMAT component h-IMRT1, h-IMRT2 and h-VMAT1, h-VMAT2, respectively. HTs were compared with 3D-CRT in terms of HI and TC for PTV, and total lung TL and contralateral lung CL V5Gy, V10Gy, V20Gy and mean lung dose MLD. Results: All HTs were advantageous for HI and TC, while disadvantageous for TL and CL-V5Gy. H-IMRT2 provided better TC than h-IMRT1, and so did h-VMAT2 compared to h-VMAT1. Lower weighting of IMRTVMAT decreased TL and CL-V5Gy in HTs. In addition, h-IMRT1 decreased TL and CL-MLD and CL-V20Gy compared to h-IMRT2, while h-VMAT2 decreased TL-V20Gy and CL-MLD compared to h-VMAT2. Conclusion: In the RT of lung tumors close to vertebra, it may be appropriate to suggest a ratio of IMRTVMAT component about 10 in order to decrease the low and intermediate dose-wash lung volume, if HI and TC values are acceptable.

 Purpose: Its postulated that hybrid techniques HT with lower weighting of IMRTVMAT component would improve lung dose-volume parameters despite some disadvantage in PTV homogeneity index HI and target coverage TC. Material and Methods: Conformal plans were prepared using 6-10-15 MV-X photon energies while IMRTVMAT plans of HTs were prepared using 6MV-X. Four HTs were developed having two different ratios 10 and 50 of IMRTVMAT component h-IMRT1, h-IMRT2 and h-VMAT1, h-VMAT2, respectively. HTs were compared with 3D-CRT in terms of HI and TC for PTV, and total lung TL and contralateral lung CL V5Gy, V10Gy, V20Gy and mean lung dose MLD. Results: All HTs were advantageous for HI and TC, while disadvantageous for TL and CL-V5Gy. H-IMRT2 provided better TC than h-IMRT1, and so did h-VMAT2 compared to h-VMAT1. Lower weighting of IMRTVMAT decreased TL and CL-V5Gy in HTs. In addition, h-IMRT1 decreased TL and CL-MLD and CL-V20Gy compared to h-IMRT2, while h-VMAT2 decreased TL-V20Gy and CL-MLD compared to h-VMAT2. Conclusion: In the RT of lung tumors close to vertebra, it may be appropriate to suggest a ratio of IMRTVMAT component about 10 in order to decrease the low and intermediate dose-wash lung volume, if HI and TC values are acceptable.

Makale detayları

Comparison of Hybrid Techniques with 3D-Conformal Radiotherapy in Patients with Lung Cancer

Yazarlar:

Ömer Azaklıoğlu | Doğukan Akçay | İlhami Er | Kadir Akgüngör | Ayşe Nur Demiral

Yayıncı:

Dokuz Eylul University

Ana Başlıklar:

Health Care Administration

Dergi:

Journal of Basic and Clinical Health Sciences Vol.7 Issue 3, pp.50-57

Belge Tipi:

Makale

Yayın Tarihi:

9/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001299969

pISSN:

2564-7288

lung cancer

radiotherapy

treatment planning

hybrid technique

volumetric modulated arc therapy

intensity modulated radiation therapy

Sayı

Makale detayları

Comparison of Hybrid Techniques with 3D-Conformal Radiotherapy in Patients with Lung Cancer

Yazarlar: Ömer Azaklıoğlu | Doğukan Akçay | İlhami Er | Kadir Akgüngör | Ayşe Nur Demiral

Yayıncı: Dokuz Eylul University

Ana Başlıklar: Health Care Administration

Dergi: Journal of Basic and Clinical Health Sciences Vol.7 Issue 3, pp.50-57

Belge Tipi: Makale

Yayın Tarihi: 9/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001299969

pISSN: 2564-7288

lung cancer

radiotherapy

treatment planning

hybrid technique

volumetric modulated arc therapy

intensity modulated radiation therapy

Sayı

Yazarlar:

Ömer Azaklıoğlu | Doğukan Akçay | İlhami Er | Kadir Akgüngör | Ayşe Nur Demiral

Yayıncı:

Dokuz Eylul University

Ana Başlıklar:

Health Care Administration

Dergi:

Journal of Basic and Clinical Health Sciences Vol.7 Issue 3, pp.50-57

Belge Tipi:

Makale

Yayın Tarihi:

9/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001299969

pISSN:

2564-7288