Emergency cholecystectomy vs. percutaneous cholecystostomy for acute cholecystitis in high-risk patients: a comparison of mortality and clinical outcomes

Ümit Özdemir; Gamze Kızıltan; Abdullah Fatih Sancak; Azad Hekimoğlu

Makale detayları

Emergency cholecystectomy vs. percutaneous cholecystostomy for acute cholecystitis in high-risk patients: a comparison of mortality and clinical outcomes

Yazarlar:

Ümit Özdemir | Gamze Kızıltan | Abdullah Fatih Sancak | Azad Hekimoğlu

Yayıncı:

Cukurova University

Ana Başlıklar:

Gastroenteroloji Cerrahisi | Genel Cerrahi

Dergi:

Cukurova Medical Journal Vol.50 Issue 2, pp.279-286

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001351457

pISSN:

2602-3032

Anahtar kelimeler:

Özet:

 Purpose: The aim of this study was to compare emergency cholecystectomy EC and percutaneous cholecystectomy PC in high-risk acute cholecystitis patients in respect of mortality and other clinical characteristics. Material and Methods: A retrospective examination was made of patients graded as ASAPS3 who underwent EC or PC because of acute cholecystitis. The two groups were compared in terms of demographic characteristics, mortality, complications, re-admission, and re-intervention rates. Results: Patients in the PC group were older 78.119.76 vs 71.6912.56 years and had more frequent comorbidities 99.1 ve 89.7. Both groups were similar in terms of gender distribution, complication rates and severity Clavien-Dindo, re-admission rates, and length of stay in hospital. The need for re-intervention was greater in the PC group 30.2 vs.3.4. Mortality rates were higher in the PC group 40.5 vs.6.9. Independent predictive factors of mortality were determined to be the application of PC in treatment odds ratio:8.756 and older age odds ratio: 1.133. Conclusion: In patients with high-risk acute cholecystitis, EC is superior to PC in terms of lower mortality and reducing the need for re-intervention. Research should be continued for subgroups of patients such as those with biliary sepsis, in intensive care, or with early cholecystectomy bridging.

 Purpose: The aim of this study was to compare emergency cholecystectomy EC and percutaneous cholecystectomy PC in high-risk acute cholecystitis patients in respect of mortality and other clinical characteristics. Material and Methods: A retrospective examination was made of patients graded as ASAPS3 who underwent EC or PC because of acute cholecystitis. The two groups were compared in terms of demographic characteristics, mortality, complications, re-admission, and re-intervention rates. Results: Patients in the PC group were older 78.119.76 vs 71.6912.56 years and had more frequent comorbidities 99.1 ve 89.7. Both groups were similar in terms of gender distribution, complication rates and severity Clavien-Dindo, re-admission rates, and length of stay in hospital. The need for re-intervention was greater in the PC group 30.2 vs.3.4. Mortality rates were higher in the PC group 40.5 vs.6.9. Independent predictive factors of mortality were determined to be the application of PC in treatment odds ratio:8.756 and older age odds ratio: 1.133. Conclusion: In patients with high-risk acute cholecystitis, EC is superior to PC in terms of lower mortality and reducing the need for re-intervention. Research should be continued for subgroups of patients such as those with biliary sepsis, in intensive care, or with early cholecystectomy bridging.

 Purpose: The aim of this study was to compare emergency cholecystectomy EC and percutaneous cholecystectomy PC in high-risk acute cholecystitis patients in respect of mortality and other clinical characteristics. Material and Methods: A retrospective examination was made of patients graded as ASAPS3 who underwent EC or PC because of acute cholecystitis. The two groups were compared in terms of demographic characteristics, mortality, complications, re-admission, and re-intervention rates. Results: Patients in the PC group were older 78.119.76 vs 71.6912.56 years and had more frequent comorbidities 99.1 ve 89.7. Both groups were similar in terms of gender distribution, complication rates and severity Clavien-Dindo, re-admission rates, and length of stay in hospital. The need for re-intervention was greater in the PC group 30.2 vs.3.4. Mortality rates were higher in the PC group 40.5 vs.6.9. Independent predictive factors of mortality were determined to be the application of PC in treatment odds ratio:8.756 and older age odds ratio: 1.133. Conclusion: In patients with high-risk acute cholecystitis, EC is superior to PC in terms of lower mortality and reducing the need for re-intervention. Research should be continued for subgroups of patients such as those with biliary sepsis, in intensive care, or with early cholecystectomy bridging.

 Amaç: Bu çalışma ile yüksek riskli akut kolesistit hastalarında mortalite ve diğer klinik özellikleri açısından acil kolesistektomiEC ile perkütan kolesistostomiyi PC karşılaştırmayı amaçladık. Gereç ve Yöntem: Akut kolesistit nedeniyle acil kolesistektomiEC veya perkütan kolesistostomiPC uygulanan ASAPS3 hastalar retrospektif incelendi. Demografik özellikler, mortalite, komplikasyonlar, readmission, reintervention oranları karşılaştırıldı. Bulgular: PC grubunda yaş daha yüksektir 78.119.76 ve 71.6912.56 yıl, daha sık komorbid bir durum görülmektedir 99.1 ve 89.7. Cinsiyet dağılımı, komplikasyon sıklığı, komplikasyonların ciddiyeti Clavien-Dindo,tekrar yatış sıklığı ve yatış süresi gruplar arasında benzerdir. PCde daha fazla yeniden müdahaleye ihtiyaç duyuldu30.2 vs 3.4. Mortalite, PC grubunda daha fazladır, 40.5 vs 6.9, Tedavide PC uygulanması odds ratio:8.756 ve yüksek yaş odds ratio: 1.133 mortalitenin bağımsız yordayıcı faktörleridir. Sonuç: Yüksek riskli akut kolesistit hastalarında EC mortalite ve reinterventionu azaltır, PCye göre üstündür. Bilier sepsis, yoğun bakım hastaları, erken dönem kolesistektomiye köprüleme gibi alt gruplar için araştırmalara devam edilmelidir.

Makale detayları

Emergency cholecystectomy vs. percutaneous cholecystostomy for acute cholecystitis in high-risk patients: a comparison of mortality and clinical outcomes

Yazarlar:

Ümit Özdemir | Gamze Kızıltan | Abdullah Fatih Sancak | Azad Hekimoğlu

Yayıncı:

Cukurova University

Ana Başlıklar:

Gastroenteroloji Cerrahisi | Genel Cerrahi

Dergi:

Cukurova Medical Journal Vol.50 Issue 2, pp.279-286

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001351457

pISSN:

2602-3032

Acute Cholecystitis

Emergency Cholecystectomy

Percutaneus Cholecystostomy

High Risk

MortalityAkut Kolesistit

Acil Kolesistektomi

Perkütan kolesistostomi

Yüksek Risk

Mortalite

Sayı

Makale detayları

Yazarlar: Ümit Özdemir | Gamze Kızıltan | Abdullah Fatih Sancak | Azad Hekimoğlu

Yayıncı: Cukurova University

Ana Başlıklar: Gastroenteroloji Cerrahisi | Genel Cerrahi

Dergi: Cukurova Medical Journal Vol.50 Issue 2, pp.279-286

Belge Tipi: Makale

Yayın Tarihi: 6/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001351457

pISSN: 2602-3032

Sayı

Yazarlar:

Ümit Özdemir | Gamze Kızıltan | Abdullah Fatih Sancak | Azad Hekimoğlu

Yayıncı:

Cukurova University

Ana Başlıklar:

Gastroenteroloji Cerrahisi | Genel Cerrahi

Dergi:

Cukurova Medical Journal Vol.50 Issue 2, pp.279-286

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001351457

pISSN:

2602-3032