Facile and rapid synthesis of some novel polysubstituted imidazoles by employing magnetic Fe3O4 nanoparticles as a high efficient catalyst

Bahador KARAMI; Khalil ESKANDARI; Abdolmohammad GHASEMI

Makale detayları

Facile and rapid synthesis of some novel polysubstituted imidazoles by employing magnetic Fe3O4 nanoparticles as a high efficient catalyst

Yazarlar:

Bahador KARAMI | Khalil ESKANDARI | Abdolmohammad GHASEMI

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2012 Vol.36 Issue 4, pp.601-613

Belge Tipi:

Makale

Yayın Tarihi:

3/2012

Belge Dili:

Türkçe

Document ID (Org No.):

2000727597

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

Multicomponent, one-pot, highly efficient, and  environmentally adapted synthesis of some novel polysubstituted  imidazoles by the use of various aldehydes, benzil, aliphatic, and  aromatic primary amines and ammonium acetate in the presence of  Fe3O4 nanoparticles as catalyst under solvent-free condition is  explained.  A highly efficient role of Fe3O4 nanoparticles as  catalyst in this synthesis was shown.  By this advantage, several  polysubstituted imidazoles as pharmaceutical important molecules can  be prepared in high yield and high purity.  This method is very easy  and rapid for the synthesis of imidazole derivatives.  All products  were deduced from their IR and NMR spectroscopic data.  The Fe3O4  nanoparticles were characterized by powdered X-ray diffraction (XRD),  transmission electron microscopy (TEM), and FT-IR spectroscopy.

 

Multicomponent, one-pot, highly efficient, and  environmentally adapted synthesis of some novel polysubstituted  imidazoles by the use of various aldehydes, benzil, aliphatic, and  aromatic primary amines and ammonium acetate in the presence of  Fe3O4 nanoparticles as catalyst under solvent-free condition is  explained.  A highly efficient role of Fe3O4 nanoparticles as  catalyst in this synthesis was shown.  By this advantage, several  polysubstituted imidazoles as pharmaceutical important molecules can  be prepared in high yield and high purity.  This method is very easy  and rapid for the synthesis of imidazole derivatives.  All products  were deduced from their IR and NMR spectroscopic data.  The Fe3O4  nanoparticles were characterized by powdered X-ray diffraction (XRD),  transmission electron microscopy (TEM), and FT-IR spectroscopy.

Makale detayları

Facile and rapid synthesis of some novel polysubstituted imidazoles by employing magnetic Fe3O4 nanoparticles as a high efficient catalyst

Yazarlar: Bahador KARAMI | Khalil ESKANDARI | Abdolmohammad GHASEMI

Yayıncı: TUBITAK

Dergi: Turkish Journal of Chemistry 2012 Vol.36 Issue 4, pp.601-613

Belge Tipi: Makale

Yayın Tarihi: 3/2012

Belge Dili: Türkçe

Document ID (Org No.): 2000727597

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Bahador KARAMI | Khalil ESKANDARI | Abdolmohammad GHASEMI

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2012 Vol.36 Issue 4, pp.601-613

Belge Tipi:

Makale

Yayın Tarihi:

3/2012

Belge Dili:

Türkçe

Document ID (Org No.):

2000727597

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527