DNA- Binding, Biological Activities, and Chemical Composition of Wild Growing Epilobium angustifolium L. Extracts from Canakkale, Turkey

Aysema SAYIK; Ayşe Sergüzel YUSUFOĞLU; Leyla AÇIK; Gülen TÜRKER; Betül AYDIN; Leyla ARSLAN

doi:https://doi.org/10.18596/jotcsa.319789

Makale detayları

DNA- Binding, Biological Activities, and Chemical Composition of Wild Growing Epilobium angustifolium L. Extracts from Canakkale, Turkey

Yazarlar:

Aysema SAYIK | Ayşe Sergüzel YUSUFOĞLU | Leyla AÇIK | Gülen TÜRKER | Betül AYDIN | Leyla ARSLAN

Yayıncı:

Turkish Chemical Society

Ana Başlıklar:

Kimya mühendisliği | Uygulamalı fizik

Dergi:

Journal of the Turkish Chemical Society Section A: Chemistry 2017 Vol.4 Issue 3, pp.811-840

Belge Tipi:

Makale

Yayın Tarihi:

8/2017

Belge Dili:

İngilizce

Document ID (Org No.):

2000503494

Sıklık:

Üç Aylık

eISSN:

2149-0120

DOI:

https://doi.org/10.18596/jotcsa.319789

Özet:

 




The usage of Epilobium
angustifolium L. in folk medicine against prostate and skin diseases encouraged
us to investigate pBR322 DNA-binding ability, biological activities and
chemical composition of wild growing Epilobium
angustifolium L.’s methanolic, ethanolic and aqueous extracts from
Canakkale, Turkey. DNA-binding activity was studied by agarose gel
electrophoresis and chemical composition via GC, GC-MS, HPLC, LC-MS, ICP-MS and
AAS. Literature survey indicates no data on pBR322 plasmid DNA interaction of Epilobium species which is an important
criteria for being a potential anticancer agent. Antibacterial and antifungal
effects were tested against 11 bacterias and 3 fungis and compared with
ampicillin, chloramphenicol and ketokanozol by agar well diffusion techniques. Total
phenolic content was found by Folin-Ciocalteu method and antioxidant activity
was obtained by DPPH and Fe (II)-FZ (ferric-ferrozine)  methods. This plant is rich of flavonoids,  hormones, 
fatty and phenolic acids. Si, K, 
Mg, P and Mn were the main inorganic elements. Epilobium angustifolium L. with its high DNA-binding activity and
rich chemical composition can be a good potential anticancer, antimicrobial and
antioxidant prodrug.  

.

Makale detayları

DNA- Binding, Biological Activities, and Chemical Composition of Wild Growing Epilobium angustifolium L. Extracts from Canakkale, Turkey

Yazarlar: Aysema SAYIK | Ayşe Sergüzel YUSUFOĞLU | Leyla AÇIK | Gülen TÜRKER | Betül AYDIN | Leyla ARSLAN

Yayıncı: Turkish Chemical Society

Ana Başlıklar: Kimya mühendisliği | Uygulamalı fizik

Dergi: Journal of the Turkish Chemical Society Section A: Chemistry 2017 Vol.4 Issue 3, pp.811-840

Belge Tipi: Makale

Yayın Tarihi: 8/2017

Belge Dili: İngilizce

Document ID (Org No.): 2000503494

Sıklık: Üç Aylık

eISSN: 2149-0120

DOI: https://doi.org/10.18596/jotcsa.319789

Sayı

Yazarlar:

Aysema SAYIK | Ayşe Sergüzel YUSUFOĞLU | Leyla AÇIK | Gülen TÜRKER | Betül AYDIN | Leyla ARSLAN

Yayıncı:

Turkish Chemical Society

Ana Başlıklar:

Kimya mühendisliği | Uygulamalı fizik

Dergi:

Journal of the Turkish Chemical Society Section A: Chemistry 2017 Vol.4 Issue 3, pp.811-840

Belge Tipi:

Makale

Yayın Tarihi:

8/2017

Belge Dili:

İngilizce

Document ID (Org No.):

2000503494

Sıklık:

Üç Aylık

eISSN:

2149-0120

DOI:

https://doi.org/10.18596/jotcsa.319789