Mortality predictors of patients suffering of acute pancreatitis and development of intraabdominal hypertension

Maja STOJANOVIC; Petar SVORCAN; Aleksandar KARAMARKOVIC; Nebojsa LADJEVIC; Radmilo JANKOVIC; Predrag STEVANOVIC

Makale detayları

Mortality predictors of patients suffering of acute pancreatitis and development of intraabdominal hypertension

Yazarlar:

Maja STOJANOVIC | Petar SVORCAN | Aleksandar KARAMARKOVIC | Nebojsa LADJEVIC | Radmilo JANKOVIC | Predrag STEVANOVIC

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 2, pp.506-513

Belge Tipi:

Makale

Yayın Tarihi:

3/2019

Belge Dili:

Türkçe

Document ID (Org No.):

2000750172

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Özet:

 

Background/aim: Intraabdominal hypertension (IAH) occurs frequently in patients with acute pancreatitis and adds to their morbidity and mortality. The main aim of the study was to identify the determination of the predictive factors connected to IAH that influence the evolution of acute pancreatitis. Materials and methods: The prospective cohort study was conducted on 100 patients who had acute pancreatitis. According to obtained intraabdominal pressure (IAP) values, the patients were divided into two groups: one group (n = 40) with normal IAP values and the other  (IAH  group,  n  =  60)  with  increased  IAP  values.  Deceased  patients  were  specially  analyzed  within  the  IAH  group  in  order  to  determine mortality predictors. Results: Statistical significance of IAP (P = 0.048), lactates (P = 0.048), peak pressure (P = 0.043), abdominal perfusion pressure (P = 0.05),  and  mean  arterial  pressure  (P  =  0.041)  was  greater  for  deceased  than  for  surviving  patients  in  the  IAH  group.  High  mortality  appears for patients younger than 65 years old, with lactate level higher than 3.22 mmol/L and filtration gradient (GF) lower than 67 mmHg. Conclusion: Age, lactates, GF, and APACHE II score are determined as mortality predictors for patients suffering from acute pancreatitis who developed IAH. The mortality rate is higher when the level of GF is decreasing and the level of lactate increasing.

Makale detayları

Mortality predictors of patients suffering of acute pancreatitis and development of intraabdominal hypertension

Yazarlar: Maja STOJANOVIC | Petar SVORCAN | Aleksandar KARAMARKOVIC | Nebojsa LADJEVIC | Radmilo JANKOVIC | Predrag STEVANOVIC

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2019 Vol.49 Issue 2, pp.506-513

Belge Tipi: Makale

Yayın Tarihi: 3/2019

Belge Dili: Türkçe

Document ID (Org No.): 2000750172

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Maja STOJANOVIC | Petar SVORCAN | Aleksandar KARAMARKOVIC | Nebojsa LADJEVIC | Radmilo JANKOVIC | Predrag STEVANOVIC

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 2, pp.506-513

Belge Tipi:

Makale

Yayın Tarihi:

3/2019

Belge Dili:

Türkçe

Document ID (Org No.):

2000750172

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144