Depression and Parkinson disease: prevalence, temporal relationship, and determinants

Hale Yapici ESER; Hatice Ayşe BORA; Asli KURUOĞLU

Makale detayları

Depression and Parkinson disease: prevalence, temporal relationship, and determinants

Yazarlar:

Hale Yapici ESER | Hatice Ayşe BORA | Asli KURUOĞLU

Yayıncı:

TUBITAK

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Turkish Journal of Medical Sciences 2017 Vol.47 Issue 2, pp.499-503

Belge Tipi:

Makale

Yayın Tarihi:

3/2017

Belge Dili:

İngilizce

Document ID (Org No.):

2000751429

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Özet:

 

Background/aim: Comorbidity of depression in Parkinson disease (PD) is a major factor that changes patients? quality of life. However,  the neurobiological and sociodemographic risk factors for this comorbidity are not well studied. In this study, we aimed to define the  prevalence, temporal relationship, and psychosocial and clinical determinants of depression comorbid with PD.  Materials and methods: Fifty-five PD patients were evaluated with SCID, a data form that assessed sociodemographic and PD-related  variables, UPDRS III, HAM-D, HAM-A, MMSE, and the Apathy Evaluation Scale.  Results: Depression (lifetime: 45.5%, last month: 25.5%, before PD: 20%) was the most frequent psychiatric diagnosis. The major  determinants of depression in the last month and depression before PD were early onset of PD and young age. Patients on pramipexole  treatment were less likely to be diagnosed with depression in the last month. Other sociodemographic and PD-related variables were not  significantly different for lifetime, last month, and pre-PD depression diagnosis compared to their counterparts.  Conclusion: Depression is prevalent both before and after patient gets a PD diagnosis. Depression is not only the result of PD-related  life changes but it is also a preceding factor that may decrease the age of PD onset.

Makale detayları

Depression and Parkinson disease: prevalence, temporal relationship, and determinants

Yazarlar: Hale Yapici ESER | Hatice Ayşe BORA | Asli KURUOĞLU

Yayıncı: TUBITAK

Ana Başlıklar: Sağlık teşvikleri

Dergi: Turkish Journal of Medical Sciences 2017 Vol.47 Issue 2, pp.499-503

Belge Tipi: Makale

Yayın Tarihi: 3/2017

Belge Dili: İngilizce

Document ID (Org No.): 2000751429

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Hale Yapici ESER | Hatice Ayşe BORA | Asli KURUOĞLU

Yayıncı:

TUBITAK

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Turkish Journal of Medical Sciences 2017 Vol.47 Issue 2, pp.499-503

Belge Tipi:

Makale

Yayın Tarihi:

3/2017

Belge Dili:

İngilizce

Document ID (Org No.):

2000751429

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144